ChemicalBook > CAS DataBase List > N-(4-Hydroxymethylbenzyl) Cyclam
N-(4-Hydroxymethylbenzyl) Cyclam
- Product Name
- N-(4-Hydroxymethylbenzyl) Cyclam
- CAS No.
- 176252-20-3
- Chemical Name
- N-(4-Hydroxymethylbenzyl) Cyclam
- Synonyms
- Plerixafor-5;Pulesafu impurity 5;Reaxys ID: 18177330;Plerixafor Impurity E;Plerixafor Impurity 25;Plerixafor Impurity 1 TetraHCl;N-(4-Hydroxymethylbenzyl) Cyclam;N-(4-Hydroxymethylbenzyl) Cyclam TetraHCl;4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)-Benzenemethanol;Benzenemethanol, 4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)-
- CBNumber
- CB43116441
- Molecular Formula
- C18H32N4O
- Formula Weight
- 320.47
- MOL File
- 176252-20-3.mol
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N-(4-Hydroxymethylbenzyl) Cyclam Property
- Boiling point:
- 496.9±45.0 °C(Predicted)
- Density
- 1.002±0.06 g/cm3(Predicted)
- pka
- 14.44±0.10(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- H945945
- Product name
- N-(4-Hydroxymethylbenzyl)Cyclam
- Packaging
- 5mg
- Price
- $345
- Updated
- 2021/12/16
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N-(4-Hydroxymethylbenzyl) Cyclam Chemical Properties,Usage,Production
Uses
N-(4-Hydroxymethylbenzyl) Cyclam is an impurity of Plerixafor (P580500), a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin''s lymphoma (NHL) and multiple myeloma (MM).
N-(4-Hydroxymethylbenzyl) Cyclam Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(4-Hydroxymethylbenzyl) Cyclam Suppliers
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176252-20-3, N-(4-Hydroxymethylbenzyl) CyclamRelated Search:
Plerixafor Impurity 5
1,8-bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl) benzyl)-1,4,8,11-tetraazacyclotetradecane dodecahydrochloride
1,8-bis(4-((1,4,8,11-tetraazacyclotetradecan-4,8,11-trifluoroacetyl- 1-yl)methyl)benzyl)-4,11-difluoroacetyl-1,4,8,11- tetraazacyclotetradecane
Plerixafor Impurity B
1,4-bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)- 1,4,8,11-tetraazacyclotetradecane dodecahydrochloride
1,1'-(1,4,8,11-tetraazacyclotetradecane-1,8-diyl)bis(2,2,2-
trifluoroethan-1-one) dihydrochloride
1,11-bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane
1,4,8,11- tetra(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane
4-((4,8,11-tris(2,2,2-trifluoroacetyl)-1,4,8,11- tetraazacyclotetradecan-1-yl)methyl)benzaldehyde
1-(1,4,8,11-tetraazacyclotetradecan-1-yl)-2,2,2-trifluoroethan-1-one trihydrochloride
1,1',1''-(1,4,8,11-tetraazacyclotetradecane-1,4,8-triyl)tris(2,2,2- trifluoroethanone) hydrochloride
1,8-bis(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1,4,8,11-tetraazacyclotetradecane
Plerixafor Impurity A
1-(4,8-bis-(2,2,2-trifluoroacetyl)-11-{4-[4,8,11-tris-(2,2,2-trifluoroacetyl)-1,4,8,11-tetraazacyclotetradec-1-ylMethyl]-benzyl}-1,4,8,11-tetraazacyclotetradec-1-yl)-2,2,2-trifluoroethanone
(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)phenyl)methanol trihydrochloride
1,1'-(1,4,8,11-tetraazacyclotetradecane-1,4-diyl)bis(2,2,2- trifluoroethan-1-one) dihydrochloride
1-tosyl-1,4,8,11-tetraazacyclotetradecane trihydrochloride
1,1',1''-(11-(4-(hydroxymethyl)benzyl)-1,4,8,11- tetraazacyclotetradecane-1,4,8-triyl)tris(2,2,2-trifluoroethan-1-one)