CRUFOMATE Property

Melting point:

60℃

Boiling point:

bp0.01 117-118°

Density 

1.176

refractive index 

nD20 1.5142

form 

solid

pka

0.05±0.70(Predicted)

Water Solubility 

4.975g/L(temperature not stated)

EPA Substance Registry System

Crufomate (299-86-5)

Safety

Hazard Codes 

Xn,N

Risk Statements 

21/22-50/53

Safety Statements 

36/37-60-61

RIDADR 

UN2783 (solid)

OEB

B

OEL

TWA: 5 mg/m3, STEL: 20 mg/m3

HS Code 

29299090

Hazardous Substances Data

299-86-5(Hazardous Substances Data)

Toxicity

LD50 in male, female rats (mg/kg): 635, 460 orally (Gaines)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

CRUFOMATE Chemical Properties,Usage,Production

Description

Crufomate is a white crystalline solid; thecommercial product is a yellow oil. Molecularweight=291.71; Boiling point=(decomposes); Freezing/Melting point=(decomposes) 63℃. Insoluble in water.

Chemical Properties

Crufomate is a white crystalline solid; the commercial product is a yellow oil.

Uses

Systemic insecticide and anthelmintic.

Uses

Crufomate is an organophosphate pesticide. Crufomate is an anthelmintic that functions as a potent inhibitor of an acetylcholinesterase in the anterior end of the worms. Crufomate is also used to combat bovine hypodermatosis.

Definition

ChEBI: Crufomate is an alkylbenzene.

General Description

White crystalline solid Mp: 61.5°C. The commercial product is a yellow oil. A phosphoramidate insecticide.

Reactivity Profile

CRUFOMATE is combustible; liquid formulations containing organic solvents may be flammable. Incompatible with strongly basic and strongly acidic materials. Unstable over long periods in aqueous preparations or above140°F. Emits toxic fumes of POx, Cl2 and NOx when heated to decomposition (Hazardous Chemicals Desk Reference p. 272 (1987)).

Hazard

Cholinesterase inhibitor. Questionable carcinogen.

Agricultural Uses

Insecticide, Anthelmintic (for cattle): All residue limits for crufomate, as listed in 40 CFR 180.295, were revoked by the U.S. EPA on June 9, 1993. All registered uses of crufomate in or on fat, meat, and meat byproducts of cattle, goats, and sheep were canceled It is applied as a spray on plants to kill insects, grubs, and worms on cattle. Not listed for use in EU countries

Trade name

DOWCO® 132[C]; MONTREL®[C]; RUELENE®[C]; DRENCH®[C]; RULENE®[C]

Potential Exposure

A potential danger to those involved in the manufacture, formulation, and application of this insecticide and anthelmintic for cattle.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If thischemical has been inhaled, remove from exposure, beginrescue breathing (using universal precautions, includingresuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24-36 h.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool wellventilated area away from heat. Also, avoid contact withoxidizers (such as peroxides, permanganates, chlorates, perchlorates, and nitrates).

Shipping

UN2783 Organophosphorus pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Contact with oxidizers may cause the release of phosphorous oxides. Contact with strong reducing agents, such as hydrides, may cause the formation of flammable and toxic phosphine gas. Decomposes on heating, forming corrosive and toxic fumes of hydrogen chloride and nitrogen and phosphorous oxides. Incompatible with strongly alkaline and strongly acidic media. Unstable over long periods in aqueous preparations or above 60°C.

Waste Disposal

Crufomate decomposes above pH 7.0 in alkaline media. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office