ChemicalBook > CAS DataBase List > 3PO

3PO

Product Name
3PO
CAS No.
13309-08-5
Chemical Name
3PO
Synonyms
(E/Z)-3PO;(E)3PO,(E) 3PO;(E)-3PO, 10 mM in DMSO;3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one;2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-
CBNumber
CB43119750
Molecular Formula
C13H10N2O
Formula Weight
210.23
MOL File
13309-08-5.mol
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3PO Property

Melting point:
144-147°C
Boiling point:
387.8±42.0 °C(Predicted)
Density 
1.192±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
4.20±0.12(Predicted)
form 
Solid
color 
Pale Yellow to Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P993045
Product name
3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
Packaging
50mg
Price
$250
Updated
2021/12/16
AK Scientific
Product number
3080CP
Product name
3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
Packaging
50mg
Price
$347
Updated
2021/12/16
AK Scientific
Product number
3080CP
Product name
3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
Packaging
10mg
Price
$163
Updated
2021/12/16
ApexBio Technology
Product number
B4939
Product name
3PO
Packaging
5mg
Price
$90
Updated
2021/12/16
ApexBio Technology
Product number
B4939
Product name
3PO
Packaging
10mg
Price
$135
Updated
2021/12/16
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3PO Chemical Properties,Usage,Production

Uses

3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one inhibits human bladder cancer cell lines growth. It also inhibits cancer cell growth proliferation by it’s treatment in combination with phenoformin. An inhibitor of 6-phosphofructo-2- kinaselfructose-2,6-bisphosphatase 3 (PFKFB).

Definition

ChEBI: 3PO is a member of the class of pyridines that is pyridine substituted by a 3-oxo-3-(pyridin-4-yl)prop-1-en-1-yl group at position 3. An inhibitor of PFKFB3 kinase, an enzyme with a key role in glycolysis. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an autophagy inducer, an apoptosis inducer and an EC 2.7.1.105 (6-phosphofructo-2-kinase) inhibitor. It is a member of pyridines and an enone.

storage

Store at -20°C

3PO Preparation Products And Raw materials

Raw materials

Preparation Products

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13309-08-5, 3PORelated Search:


  • 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one
  • 2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-
  • (E)3PO,(E) 3PO
  • (E)-3PO, 10 mM in DMSO
  • (E/Z)-3PO
  • 13309-08-5