ChemicalBook > CAS DataBase List > 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid

3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid

Product Name: 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid
CAS No.: 1371587-51-7
Chemical Name: 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid
Synonyms: Cavosonstat, 10 mM in DMSO;3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid;Benzoic acid, 3-chloro-4-(6-hydroxy-2-quinolinyl)-
CBNumber: CB43129177
Molecular Formula: C16H10ClNO3
Formula Weight: 299.71
MOL File: 1371587-51-7.mol

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3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid Property

Boiling point:: 527.5±50.0 °C(Predicted)
Density: 1.462±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 2.70±0.10(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid Chemical Properties,Usage,Production

Uses

Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research[1].

References

[1] Scott H Donaldson, et al. Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR. J Cyst Fibros. 2017 May;16(3):371-379. DOI:10.1016/j.jcf.2017.01.009

3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1371587-51-7, 3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acidRelated Search:

3-chloro-4-(6-hydroxyquinolin-2-yl)benzoic acid

Benzoic acid, 3-chloro-4-(6-hydroxy-2-quinolinyl)-

Cavosonstat, 10 mM in DMSO

1371587-51-7