ethyl(1R,2S,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride
- Product Name
- ethyl(1R,2S,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride
- CAS No.
- 1626394-43-1
- Chemical Name
- ethyl(1R,2S,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride
- Synonyms
- EOS-60365;(2S,3S)-3-(ethoxycarbonyl)bicyclo[2.2.2]octan-2-aminium chloride;ethyl (2S,3S)-3-aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride;(2S,3S)-Ethyl 3-aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride;ethyl(1R,2S,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride;ethyl (2S,3S)-3-aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride - [E83389];(2S,3S)-3-amino-Bicyclo[2.2.2]octane-2-carboxylic acid ethyl ester, hydrochloride;Bicyclo[2.2.2]octane-2-carboxylic acid, 3-amino-, ethyl ester, hydrochloride (1:1), (2S,3S)-
- CBNumber
- CB43142927
- Molecular Formula
- C11H20ClNO2
- Formula Weight
- 233.74
- MOL File
- 1626394-43-1.mol
ethyl(1R,2S,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride Property
- Density
- 1.23g/cm3 at 20℃
- vapor pressure
- 0.001-0.002Pa at 20-25℃
- storage temp.
- RT, stored under nitrogen
- form
- Solid:particulate/powder
- Appearance
- White to off-white Solid
- InChI
- InChI=1/C11H19NO2.ClH/c1-2-14-11(13)9-7-3-5-8(6-4-7)10(9)12;/h7-10H,2-6,12H2,1H3;1H/t7?,8?,9-,10-;/s3
- InChIKey
- CFRFVTFZTABHIF-DOUOTPRZNA-N
- SMILES
- C([C@@H]1[C@H](C2CCC1CC2)N)(=O)OCC.Cl |&1:1,2,r|
- LogP
- -0.55 at 20℃ and pH7
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H318Causes serious eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS58399-B
- Product name
- Ethyl(2S,3S)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride
- Purity
- 97+%
- Packaging
- 250mg
- Price
- $122
- Updated
- 2021/12/16
- Product number
- CCH0065863
- Product name
- ETHYL-(2S,3S)-3-AMINOBICYCLO[2.2.2]OCTANE-2-CARBOXYLATE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $455
- Updated
- 2021/12/16
- Product number
- CD00008490
- Product name
- (2S,3S)-Ethyl3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride
- Purity
- 97%
- Packaging
- 100mg
- Price
- $62
- Updated
- 2021/12/16
- Product number
- CD00008490
- Product name
- (2S,3S)-Ethyl3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride
- Purity
- 97%
- Packaging
- 250mg
- Price
- $99
- Updated
- 2021/12/16
- Product number
- CD00008490
- Product name
- (2S,3S)-Ethyl3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $248
- Updated
- 2021/12/16
ethyl(1R,2S,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride Chemical Properties,Usage,Production
Synthesis
1626481-98-8
1626394-43-1
The general procedure for the synthesis of ethyl (2S,3S)-3-aminodicyclo[2.2.2]octane-2-carboxylate hydrochloride from the compound (CAS:1626481-98-8) is as follows: free amino esters (including (-)-1, (+)-1, (-)-2 or (+)-2, 98 mg, 5 mmol) were dissolved in anhydrous ethanol (EtOH, 100 mL ) to prepare a 0.05 M solution. Subsequently, the solution was subjected to a hydrogenation reaction in a ThalesNano H-cube TM system using 10% Pd/C as a catalyst, setting a flow rate of 1 mL/min, a reaction temperature of 50 °C, and a hydrogen pressure of 50 bar.After completion of the reaction, the ethanol was removed under vacuum. The residue was dissolved in ethanol containing 22% HCl (2 mL) and stirred for 10 min at room temperature. Finally, the target product amino ester hydrochloride was obtained by removing the solvent.
References
[1] Molecules, 2013, vol. 18, # 12, p. 15080 - 15093
ethyl(1R,2S,3S,4R)-3-aminobicyclo[2.2.2]octane-2-carboxylatehydrochloride Preparation Products And Raw materials
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