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S3QEL 2

Product Name
S3QEL 2
CAS No.
890888-12-7
Chemical Name
S3QEL 2
Synonyms
S3QEL 2;1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(3,4-dimethylphenyl)-N,N-dipropyl-;S3QEL-2，1-(3,4-dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CBNumber
CB43146374
Molecular Formula
C19H25N5
Formula Weight
323.44
MOL File
890888-12-7.mol
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S3QEL 2 Property

storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: slightly soluble
form 
A crystalline solid
color 
Off-white to yellow
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1554
Product name
S3QEL 2
Packaging
10 mg
Price
$103
Updated
2026/03/19
Sigma-Aldrich
Product number
SML1554
Product name
S3QEL 2
Packaging
50 mg
Price
$420
Updated
2026/03/19
Cayman Chemical
Product number
18556
Product name
S3QEL-2
Purity
≥98%
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
18556
Product name
S3QEL-2
Purity
≥98%
Packaging
10mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
18556
Product name
S3QEL-2
Purity
≥98%
Packaging
25mg
Price
$161
Updated
2024/03/01
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S3QEL 2 Chemical Properties,Usage,Production

Description

S3QEL-2 is a cell-permeable, selective suppressor of electron leak from mitochondrial respiratory complex III, inhibiting site IIIQo superoxide production (IC50 = 1.7 μM) without altering normal bioenergetics function. It reduces production of H2O2 during oxidation of glutamate plus malate to 25% of the control level. S3QEL-2 also protects against ROS-induced cell stress in pancreatic β-cells and decreases HIF-1α induction in response to hypoxia.

Uses

S3QEL 2 supresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation.

References

[1] ADAM L ORR. Suppressors of superoxide production from mitochondrial complex III[J]. Nature chemical biology, 2015, 11 11: 834-836. DOI: 10.1038/nchembio.1910

S3QEL 2 Preparation Products And Raw materials

Raw materials

Preparation Products

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S3QEL 2 Suppliers

China 20 United Kingdom 1 United States 7 Global 28
Shanghai Beckham Medical Technology Co., Ltd
Tel
13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
Country
China
ProdList
2519
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24960
Advantage
58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
Advantage
58
Shanghai Ken chemical Technology Co.,ltd
Tel
13701870891; 02152215958
Email
47697177@qq.com
Country
China
ProdList
10011
Advantage
58

890888-12-7, S3QEL 2Related Search:


  • 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • S3QEL 2
  • 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(3,4-dimethylphenyl)-N,N-dipropyl-
  • S3QEL-2，1-(3,4-dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • 890888-12-7