ChemicalBook > CAS DataBase List > S3QEL 2
S3QEL 2
- Product Name
- S3QEL 2
- CAS No.
- 890888-12-7
- Chemical Name
- S3QEL 2
- Synonyms
- S3QEL 2;1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(3,4-dimethylphenyl)-N,N-dipropyl-
- CBNumber
- CB43146374
- Molecular Formula
- C19H25N5
- Formula Weight
- 323.44
- MOL File
- 890888-12-7.mol
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S3QEL 2 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: slightly soluble
- form
- A crystalline solid
- color
- Off-white to yellow
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 18556
- Product name
- S3QEL-2
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $37
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18556
- Product name
- S3QEL-2
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 18556
- Product name
- S3QEL-2
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $161
- Updated
- 2024/03/01
TRC
- Product number
- S030000
- Product name
- S3QEL2
- Packaging
- 50mg
- Price
- $250
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2878CX
- Product name
- 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Packaging
- 25mg
- Price
- $276
- Updated
- 2021/12/16
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S3QEL 2 Chemical Properties,Usage,Production
Description
S3QEL-2 is a cell-permeable, selective suppressor of electron leak from mitochondrial respiratory complex III, inhibiting site IIIQo superoxide production (IC50 = 1.7 μM) without altering normal bioenergetics function. It reduces production of H2O2 during oxidation of glutamate plus malate to 25% of the control level. S3QEL-2 also protects against ROS-induced cell stress in pancreatic β-cells and decreases HIF-1α induction in response to hypoxia.
Uses
S3QEL 2 supresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation.
S3QEL 2 Preparation Products And Raw materials
Raw materials
Preparation Products
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S3QEL 2 Suppliers
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