ChemicalBook > CAS DataBase List > 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole
5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole
- Product Name
- 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole
- CAS No.
- 1570496-34-2
- Chemical Name
- 5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole
- Synonyms
- CPD1805;CS-2899;IACS-10759;IACS-10759 (IACS-010759 );IACS-010759 (IACS-10759 );IACS-010759; IACS 010759; IACS010759; IACS-10759; IACS 10759; IACS10759;5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-ox;5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole;5-[5-Methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole;Piperidine, 4-(methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]-
- CBNumber
- CB43147164
- Molecular Formula
- C25H25F3N6O4S
- Formula Weight
- 562.56
- MOL File
- 1570496-34-2.mol
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5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole Property
- Boiling point:
- 768.0±70.0 °C(Predicted)
- Density
- 1.48±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:24.23(Max Conc. mg/mL);43.07(Max Conc. mM)
DMF:0.1(Max Conc. mg/mL);0.18(Max Conc. mM) - form
- A crystalline solid
- pka
- 3.24±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 25867
- Product name
- IACS-010759
- Packaging
- 1mg
- Price
- $27
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25867
- Product name
- IACS-010759
- Packaging
- 25mg
- Price
- $236
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25867
- Product name
- IACS-010759
- Packaging
- 5mg
- Price
- $88
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25867
- Product name
- IACS-010759
- Packaging
- 10mg
- Price
- $149
- Updated
- 2024/03/01
TRC
- Product number
- M329473
- Product name
- 4-(Methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]piperidine(IACS-010759)
- Packaging
- 25mg
- Price
- $1175
- Updated
- 2021/12/16
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5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole Chemical Properties,Usage,Production
Uses
4-(Methylsulfonyl)-1-[3-[[5-methyl-3-[3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazol-5-yl]-1H-1,2,4-triazol-1-yl]methyl]phenyl]piperidine is a drug candidate that acts as a modulator of HIF activity for treatment of cancer and other hypoxia-mediated diseases.
5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole Preparation Products And Raw materials
Raw materials
Preparation Products
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5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole Suppliers
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