Luotonin F
- Product Name
- Luotonin F
- CAS No.
- 244616-85-1
- Chemical Name
- Luotonin F
- Synonyms
- Luotonin F;Luotonin F Exclusive;2-(quinoline-3-carbonyl)-1H-quinazolin-4-one;2-(3-quinolinylcarbonyl)-4(3H)-quinazolinone;4(3H)-Quinazolinone, 2-(3-quinolinylcarbonyl)-
- CBNumber
- CB43152667
- Molecular Formula
- C18H11N3O2
- Formula Weight
- 301.3
- MOL File
- 244616-85-1.mol
Luotonin F Property
- Boiling point:
- 542.0±42.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≤2.5mg/ml in DMSO;2.5mg/ml in dimethyl formamide
- form
- crystalline solid
- pka
- 2.06±0.11(Predicted)
N-Bromosuccinimide Price
- Product number
- 14254
- Product name
- Luotonin F
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 14254
- Product name
- Luotonin F
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $172
- Updated
- 2024/03/01
- Product number
- 14254
- Product name
- Luotonin F
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $299
- Updated
- 2024/03/01
- Product number
- 14254
- Product name
- Luotonin F
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $692
- Updated
- 2024/03/01
- Product number
- C4228
- Product name
- LuotoninF
- Packaging
- 10mg
- Price
- $339
- Updated
- 2021/12/16
Luotonin F Chemical Properties,Usage,Production
Biological Activity
luotonin f is an alkaloid found in the aerial parts of the peganum nigellastrum bunge, a plant which has been long used in traditional chinese medicine for the treatment of rheumatism, abscesses, and various other inflammatory conditions [1].due to their biological and pharmaceutical activities, many synthetic methods have been developed for the synthesis of luotonins. an efficient one-pot synthetic protocol has been proposed for the synthesis of luntonin f from easily available starting materials. through the rational logical design, multifundamental reactions were assembled in one-pot, such as iodination, kornblum oxidation, and annulations [2]. the developed approach could efficiently synthesize luntonin f and various analogues. luotonin f showed promising cytotoxicity against leukemia p-388 cells with an ic50 value of 2.3 μg/ml by stabilizing the dna topoisomerase i-dna complex [1].
References
[1] liang j l, cha h c, jahng y. recent advances in the studies on luotonins[j]. molecules, 2011, 16(6): 4861-4883.
[2] zhu y, fei z, liu m, et al. direct one-pot synthesis of luotonin f and analogues via rational logical design[j]. organic letters, 2012, 15(2): 378-381.
Luotonin F Preparation Products And Raw materials
Raw materials
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