MCB-613
- Product Name
- MCB-613
- CAS No.
- 296792-62-6
- Chemical Name
- MCB-613
- Synonyms
- (E/Z)-MCB-613;MCB-613 >=98% (HPLC);4-ethyl-2,6-bis(3-pyridinylmethylene)-cyclohexanone;Cyclohexanone, 4-ethyl-2,6-bis(3-pyridinylmethylene)-
- CBNumber
- CB43152672
- Molecular Formula
- C20H20N2O
- Formula Weight
- 304.39
- MOL File
- 296792-62-6.mol
MCB-613 Property
- Boiling point:
- 510.4±50.0 °C(Predicted)
- Density
- 1.159±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 2 mg/ml; DMSO: 2 mg/ml; Ethanol: 2 mg/ml
- form
- A crystalline solid
- pka
- 4.53±0.12(Predicted)
- color
- white to beige
N-Bromosuccinimide Price
- Product number
- 18315
- Product name
- MCB-613
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 18315
- Product name
- MCB-613
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $168
- Updated
- 2024/03/01
- Product number
- 18315
- Product name
- MCB-613
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $286
- Updated
- 2024/03/01
- Product number
- 18315
- Product name
- MCB-613
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $534
- Updated
- 2024/03/01
MCB-613 Chemical Properties,Usage,Production
Description
MCB-613 is a potent Steroid Receptor Coactivator Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. MCB-613 can super-stimulate SRCs' transcriptional activity. MCB-613 increases SRCs' interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS). MCB-613 selectively induce excessive stress in cancer cells. Over-stimulating the SRC oncogenic program can be an effective strategy to kill cancer cells. By integrating growth pathways on which cancer cells rely, steroid receptor coactivators (SRC-1, SRC-2, and SRC-3) represent emerging targets in cancer therapeutics.
Definition
ChEBI: MCB-613 is a cyclic ketone that is 4-ethylcyclohexanone which is substituted by pyridin-3-ylmethylene groups at positions 2 and 6. It is a potent small molecule stimulator of steroid receptor coactivators (SRCs). MCB-613 increases SRCs' interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species. Since cancer cells overexpress SRCs and rely on them for growth, MCB-613 can be used to selectively induce excessive stress in cancer cells. It has a role as a steroid receptor coactivator stimulator and an antineoplastic agent. It is a cyclic ketone, an enone and a member of pyridines.
MCB-613 Preparation Products And Raw materials
Raw materials
Preparation Products
MCB-613 Suppliers
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