ChemicalBook > CAS DataBase List > Dolutegravir Impurity 6
Dolutegravir Impurity 6
- Product Name
- Dolutegravir Impurity 6
- CAS No.
- 1357289-29-2
- Chemical Name
- Dolutegravir Impurity 6
- Synonyms
- Dotiravir Impurity 12;Dolutegravir RR Isomer;Dolutegravir Impurity 6;Doultegravirr RR Isomer;Dolutegravir Impurity 42;Dolutegravir R,R Freebase / R,R-ISomer;4-(3-chlorothiophen-2-yl)-1,3-thiazol-2-amine;(4R,12aR)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;(4R,12aS)-N-(2,5-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4, 6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine9-carboxamide;(4R,12aR)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12, 12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H- pPyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- CBNumber
- CB43154308
- Molecular Formula
- C20H19F2N3O5
- Formula Weight
- 419.38
- MOL File
- 1357289-29-2.mol
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Dolutegravir Impurity 6 Property
- Boiling point:
- 669.0±55.0 °C(Predicted)
- Density
- 1.53±0.1 g/cm3(Predicted)
- pka
- 4.50±1.00(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- D528820
- Product name
- DolutegravirRRIsomer
- Packaging
- 10mg
- Price
- $2480
- Updated
- 2021/12/16
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Dolutegravir Impurity 6 Chemical Properties,Usage,Production
Uses
Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir Impurity 6 Preparation Products And Raw materials
Raw materials
Preparation Products
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