ChemicalBook > CAS DataBase List > (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Product Name: (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
CAS No.: 1428118-39-1
Chemical Name: (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
Synonyms: Cinacalcet-16;Cinacalcet USP RC C;Cinacalcene Impurity G;Cinacalcet Related Compound C;Cinacalcet USP Related Compound C;Cinacalcet Impurity 2(Cinacalcet USP RC C);Cinacalcet Related Compound C United States Pharmacopeia (USP) Reference Standard;(R)-N-(1-(phthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-aminehydrochloride;(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride;(αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochoride Salt
CBNumber: CB43154777
Molecular Formula: C22H23ClF3N
Formula Weight: 393.88
MOL File: 1428118-39-1.mol

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(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride Property

solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Pale Beige
InChI: InChI=1/C22H22F3N.ClH/c1-16(20-10-4-8-18-7-2-3-9-21(18)20)26-15-5-6-17-11-13-19(14-12-17)22(23,24)25;/h2-4,7-14,16,26H,5-6,15H2,1H3;1H/t16-;/s3
InChIKey: DSKNQUVQQYTQFT-LSQUZMQTNA-N
SMILES: [C@H](C1=CC=CC2C=CC=CC1=2)(C)NCCCC1C=CC(C(F)(F)F)=CC=1.Cl |&1:0,r|

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Safety

HS Code: 2921490002

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Hazard and Precautionary Statements (GHS)

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(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride Chemical Properties,Usage,Production

Uses

(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochloride, is an impurity of Cinacalcet (C441800), which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels).

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1428118-39-1, (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochlorideRelated Search:

1-(1-NAPHTHYL)ETHANOL Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester (S)-(-)-1-(1-Naphthyl)ethylamine Methyl 3-(3-(trifluoroMethyl)phenyl)propanoate 1-NaphthaleneMethanaMine, 7,8-dihydro-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)- (R)-(+)-1-(1-Naphthyl)ethylamine N-(1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide 1-(7,8-dihydronaphthalen-1-yl)ethan-1-amine hydrochloride Cinacalcet IMpurity 7 1'-Acetonaphthone Cinacalcet 7,8-Dihydro Racemate HCl 3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid (αR)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl)propyl]-1-napthaleneMethanaMine-N-oxide cinacalcet iMpurity 4 1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethan-1-amine hydrochloride (R)-1-(5,6-dihydronaphthalen-1-yl)ethan-1-amine 3-(3-Trifluoromethylphenyl)propionic acid

Cinacalcet Impurity 2(Cinacalcet USP RC C)

Cinacalcet impurity 17/(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Cinacalcet-16

(R)-N-(1-(phthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-aminehydrochloride

(E)-N-(1-(7,8-dihydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide hydrochloride

Cinacalcet USP RC C

1-Naphthalenemethanamine, α-methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)

Cinacalcet USP Related Compound C

(αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethan amine Hydrochoride Salt

Cinacalcene Impurity G

Cinacalcet Related Compound C United States Pharmacopeia (USP) Reference Standard

(αR)-α-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochoride Salt

Cinacalcet para isomer-(3-(4-(trifluoromethyl)phenyl)-N-((R)-1-(naphthalen-5-yl)ethyl)propan-1-amine or (R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl) phenyl)propan-1-amine)

(alphaR)-alpha-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine Hydrochloride Salt

(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Cinacalcet Related Compound C

1428118-39-1