Etripamil
- Product Name
- Etripamil
- CAS No.
- 1593673-23-4
- Chemical Name
- Etripamil
- Synonyms
- MSP-2017;Etripamil;(-)-MSP-2017;Ca2+ channels,Calcium Channel,MSP 2017,Etripamil,inhibit,Inhibitor,MSP2017,Ca channels;Benzoic acid, 3-[2-[[(4S)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]methylamino]ethyl]-, methyl ester
- CBNumber
- CB43159974
- Molecular Formula
- C27H36N2O4
- Formula Weight
- 452.59
- MOL File
- 1593673-23-4.mol
Etripamil Property
- Boiling point:
- 593.8±50.0 °C(Predicted)
- Density
- 1.079±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Ethanol : 120 mg/mL (265.14 mM; Need ultrasonic)
- pka
- 8.92±0.50(Predicted)
- form
- Oil
- color
- Brown to wine red
- InChI
- InChI=1/C27H36N2O4/c1-20(2)27(19-28,23-11-12-24(31-4)25(18-23)32-5)14-8-15-29(3)16-13-21-9-7-10-22(17-21)26(30)33-6/h7,9-12,17-18,20H,8,13-16H2,1-6H3/t27-/s3
- InChIKey
- VAZNEHLGJGSQEL-CPAURPOUNA-N
- SMILES
- C(OC)(=O)C1=CC=CC(CCN(CCC[C@@](C#N)(C2=CC=C(OC)C(OC)=C2)C(C)C)C)=C1 |&1:15,r|
N-Bromosuccinimide Price
- Product number
- CS-0014689
- Product name
- Etripamil
- Purity
- 98.68%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-0014689
- Product name
- Etripamil
- Purity
- 98.68%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- CS-0014689
- Product name
- Etripamil
- Purity
- 98.68%
- Packaging
- 50mg
- Price
- $1650
- Updated
- 2021/12/16
- Product number
- CS-0014689
- Product name
- Etripamil
- Purity
- 98.68%
- Packaging
- 100mg
- Price
- $2650
- Updated
- 2021/12/16
Etripamil Chemical Properties,Usage,Production
Uses
Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil (MSP-2017) slows atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells[1][2].
IC 50
L-type calcium channel
References
[1] Stambler BS, et al. Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. J Am Coll Cardiol. 2018 Jul 31;72(5):489-497. DOI:10.1016/j.jacc.2018.04.082
[2] Milestone Pharmaceuticals Announces USAN Approval of Generic Name “Etripamil” for its Phase 2 Clinical Development Product for the Treatment of Paroxysmal Supraventricular Tachycardia.
Etripamil Preparation Products And Raw materials
Raw materials
Preparation Products
Etripamil Suppliers
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- 13012344321
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- China
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- United States
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