Mal-PEG1-Bromide

Product Name: Mal-PEG1-Bromide
CAS No.: 1823885-81-9
Chemical Name: Mal-PEG1-Bromide
Synonyms: Mal-PEG1-Bromide;1-(2-(2-bromoethoxy)ethyl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-[2-(2-bromoethoxy)ethyl]-;1-[2-(2-bromoethoxy)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione
CBNumber: CB43162983
Molecular Formula: C8H10BrNO3
Formula Weight: 248.07
MOL File: 1823885-81-9.mol

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Mal-PEG1-Bromide Property

Boiling point:: 358.1±22.0 °C(Predicted)
Density: 1.588±0.06 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: -2.35±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22139
Product name: Mal-PEG1-Bromide
Purity: 98%
Packaging: 500mg
Price: $560
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1501
Product name: Mal-PEG1-Bromide
Packaging: 250mg
Price: $701
Updated: 2021/12/16

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Mal-PEG1-Bromide Chemical Properties,Usage,Production

Description

Mal-PEG1-Bromide contains a maleimide group and bromide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.

Uses

Mal-PEG1-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG1-Bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG1-Bromide Suppliers

China 20 United Kingdom 1 United States 3 Global 24

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Aladdin Scientific

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Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

1823885-81-9, Mal-PEG1-BromideRelated Search:

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Mal-PEG1-Bromide

1H-Pyrrole-2,5-dione, 1-[2-(2-bromoethoxy)ethyl]-

1-[2-(2-bromoethoxy)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione

1-(2-(2-bromoethoxy)ethyl)-1H-pyrrole-2,5-dione

1823885-81-9