2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate

ChemicalBook > CAS DataBase List > 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate

Product Name: 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate
CAS No.: 1050477-43-4
Chemical Name: 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate
Synonyms: Finelidone Impurity 52;2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate;2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate;1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester;1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester (ACI)
CBNumber: CB43165232
Molecular Formula: C22H20N4O4
Formula Weight: 404.42
MOL File: 1050477-43-4.mol

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2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Property

vapor pressure: 0.006Pa at 25℃
Water Solubility: 6.2mg/L at 20℃
InChI: InChI=1S/C22H20N4O4/c1-12-11-25-21(27)19-18(15-6-5-14(10-24)9-16(15)29-3)17(13(2)26-20(12)19)22(28)30-8-4-7-23/h5-6,9,11,18,26H,4,8H2,1-3H3,(H,25,27)
InChIKey: YUBVPYQJGHKIIA-UHFFFAOYSA-N
SMILES: N1C2=C(C(=O)NC=C2C)C(C2=CC=C(C#N)C=C2OC)C(C(OCCC#N)=O)=C1C
LogP: 0.97

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Hazard and Precautionary Statements (GHS)

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2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Chemical Properties,Usage,Production

Uses

2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate is a pharmaceutical intermediary ingredient used in the preparation of Finerenone. Finerenone is a non-steroidal, selective salicorticosteroid receptor (MR) antagonist that is used to reduce the risk of serious renal and cardiac problems (e.g., decreased kidney function, end-stage renal disease, cardiovascular death, heart attack, and hospitalisation for heart failure) in patients with chronic kidney disease associated with type 2 diabetes mellitus.

Flammability and Explosibility

Not classified

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate Suppliers

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Nanjing Fred Technology Co., Ltd

Product: 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate 1050477-43-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2024-01-04

Hebei Mojin Biotechnology Co.,Ltd

Product: 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate 1050477-43-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-06-03

Xuchang Hengsheng Pharmaceutical Co., Ltd

Product: 2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate 1050477-43-4
Price: US $0.00/Kg
Min. Order: 1Kg
Purity: ≥99.0%
Supply Ability: 10 Tons
Release date: 2024-08-07

1050477-43-4, 2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylateRelated Search:

2-cyanoethyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate

1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester

2-Cyanoethyl 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-1,6-naphthyridine-3-carboxylate

1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-1,4,5,6-tetrahydro-2,8-dimethyl-5-oxo-, 2-cyanoethyl ester (ACI)

Finelidone Impurity 52

1050477-43-4

Intermediate