ChemicalBook > CAS DataBase List > Peptide 46
Peptide 46
- Product Name
- Peptide 46
- CAS No.
- 192122-40-0
- Chemical Name
- Peptide 46
- Synonyms
- PEPTIDE 46;P53 (361-382) (HUMAN);CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN);p53 (361-382) (huMan), Cellular TuMor Antigen p53 (361-382) (huMan);H-GLY-SER-ARG-ALA-HIS-SER-SER-HIS-LEU-LYS-SER-LYS-LYS-GLY-GLN-SER-THR-SER-ARG-HIS-LYS-LYS-OH;Glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-L-lysine;L-Lysine, glycyl-L-seryl-L-arginyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-histidyl-L-leucyl-L-lysyl-L-seryl-L-lysyl-L-lysylglycyl-L-glutaminyl-L-seryl-L-threonyl-L-seryl-L-arginyl-L-histidyl-L-lysyl-
- CBNumber
- CB4323244
- Molecular Formula
- C100H174N40O31
- Formula Weight
- 2432.7
- MOL File
- 192122-40-0.mol
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Peptide 46 Property
- Density
- 1.56±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- InChIKey
- KCXVFJXIDLDWKX-JEWKGGOJSA-N
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- ATG0000935
- Product name
- CELLULAR TUMOR ANTIGEN P53 (361-382) (HUMAN)
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.31
- Updated
- 2021/12/16
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Peptide 46 Chemical Properties,Usage,Production
Description
Peptide 46, a synthetic 22-mer peptide derived from the p53 C-terminal domain, can restore the growth suppressor function of mutant p53 proteins in human tumor cells. The sequence of peptide 46, which corresponds to residues 361 to 382 in the p53 C terminus, is (in one-letter code) GSRAHSSHLKSKKGQSTSRHKK[1]. Teptide 46, the only C-terminal peptide that can activate the specific DNA binding of p53, changed the mobility of the core domain, whereas the other C-terminal peptides did not. Conversely, the mobility of the C-terminal domain protein was shifted upon incubation with the core domain protein.
References
[1] G Selivanova. “Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.” Molecular and Cellular Biology 19 5 (1999): 3395–402.
Peptide 46 Preparation Products And Raw materials
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View Lastest Price from Peptide 46 manufacturers
Wuhan Xinhao Biotechnology Co., Ltd
- Product
- PEPTIDE 46 192122-40-0
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2024-01-11