(5Z)-6A-CARBAPROSTAGLANDIN I2

Product Name: (5Z)-6A-CARBAPROSTAGLANDIN I2
CAS No.: 69609-77-4
Chemical Name: (5Z)-6A-CARBAPROSTAGLANDIN I2
Synonyms: 5-CIS CARBAPROSTACYCLIN;(5Z)-6A-CARBAPROSTAGLANDIN I2;5 cis Carbaprostacyclin,5cis Carbaprostacyclin;6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID;Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-2(1H)-pentalenylidene]-, (5Z)- (9CI)
CBNumber: CB4333232
Molecular Formula: C21H34O4
Formula Weight: 350.49
MOL File: 69609-77-4.mol

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(5Z)-6A-CARBAPROSTAGLANDIN I2 Property

Boiling point:: 514.8±50.0 °C(Predicted)
Density: 1.177±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: >10 mg/ml (from 6B-PGI2); DMSO: >5 mg/ml (from 6B-PGI2); Ethanol: >20 mg/ml (from 6B-PGI2); PBS pH 7.2: >80 μg/ml (from 6B-PGI2)
form: A crystalline solid
pka: 4.77±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18211
Product name: 5-cis Carbaprostacyclin
Purity: ≥99%
Packaging: 500μg
Price: $110
Updated: 2024/03/01

Cayman Chemical

Product number: 18211
Product name: 5-cis Carbaprostacyclin
Purity: ≥99%
Packaging: 1mg
Price: $208
Updated: 2024/03/01

Cayman Chemical

Product number: 18211
Product name: 5-cis Carbaprostacyclin
Purity: ≥99%
Packaging: 5mg
Price: $558
Updated: 2021/12/16

AK Scientific

Product number: 1451AH
Product name: 5-cisCarbaprostacyclin
Packaging: 1mg
Price: $259
Updated: 2021/12/16

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(5Z)-6A-CARBAPROSTAGLANDIN I2 Chemical Properties,Usage,Production

Uses

5-cis Carbaprostacyclin is a stable analog of PGI2 based on Carbaprostacyclin (HY-112322). Carbacyclin is a PGI2 receptor agonist and vasodilator that activates PPARδ. 5-cis Carbaprostacyclin induces relaxation of pulmonary vascular tone[1][2].

Definition

ChEBI: Carbacyclin is a prostanoid.

References

[1] Kurtz M, et al. Carbaprostacyclin, a PPARdelta agonist, ameliorates excess lipid accumulation in diabetic rat placentas. Life Sci. 2010 May 22;86(21-22):781-90. DOI:10.1016/j.lfs.2010.03.008
[2] Norel X, et al. Vasoconstriction induced by activation of EP1 and EP3 receptors in human lung: effects of ONO-AE-248, ONO-DI-004, ONO-8711 or ONO-8713. Prostaglandins Other Lipid Mediat. 2004 Oct;74(1-4):101-12. DOI:10.1016/j.prostaglandins.2004.07.003

(5Z)-6A-CARBAPROSTAGLANDIN I2 Preparation Products And Raw materials

Raw materials

Preparation Products

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(5Z)-6A-CARBAPROSTAGLANDIN I2 Suppliers

China 11 United States 3 Global 14

Shanghai Aladdin Bio-Chem Technology Co.,LTD

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Shanghai YuanYe Biotechnology Co., Ltd.

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Shanghai Hongye Biotechnology Co. Ltd

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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Cayman Chemical Company

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Santa Cruz Biotechnology Inc

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Aladdin Scientific

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69609-77-4, (5Z)-6A-CARBAPROSTAGLANDIN I2Related Search:

CARBACYCLIN ETHYLIDENECYCLOOCTANE (5Z)-6A-CARBAPROSTAGLANDIN I2 VINYLCYCLOOCTANE

6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID

(5Z)-6A-CARBAPROSTAGLANDIN I2

5-CIS CARBAPROSTACYCLIN

Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-1-octenyl]-2(1H)-pentalenylidene]-, (5Z)- (9CI)

5 cis Carbaprostacyclin,5cis Carbaprostacyclin

69609-77-4