CB-7921220
- Product Name
- CB-7921220
- CAS No.
- 115453-99-1
- Chemical Name
- CB-7921220
- Synonyms
- CB-7921220;CB-7921220 (CB7921220);CB-7921220, 10 mM in DMSO;6-(4-Aminostyryl)picolinic acid;2-Pyridinecarboxylic acid, 6-[2-(4-aminophenyl)ethenyl]-
- CBNumber
- CB43333606
- Molecular Formula
- C14H12N2O2
- Formula Weight
- 240.26
- MOL File
- 115453-99-1.mol
CB-7921220 Property
- Melting point:
- 225-226 °C
- Boiling point:
- 504.3±50.0 °C(Predicted)
- Density
- 1.329±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 0.3 mg/ml
- form
- A crystalline solid
- pka
- 1.01±0.50(Predicted)
- color
- Pink to red
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 23332
- Product name
- CB-7921220
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $33
- Updated
- 2024/03/01
- Product number
- 23332
- Product name
- CB-7921220
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $143
- Updated
- 2024/03/01
- Product number
- 23332
- Product name
- CB-7921220
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $254
- Updated
- 2024/03/01
- Product number
- 23332
- Product name
- CB-7921220
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $553
- Updated
- 2024/03/01
- Product number
- CS-6954
- Product name
- CB-7921220
- Purity
- >98.0%
- Packaging
- 50mg
- Price
- $648
- Updated
- 2021/12/16
CB-7921220 Chemical Properties,Usage,Production
Description
CB-7921220 is an inhibitor of the adenylyl cyclase (AC) isoforms AC1 and AC6. It is selective, reducing AC1 and AC6 activity by 60% while having no effect on AC2 and AC5 in Sf9 membranes stimulated by forskolin when used at a concentration of 100 μM.
Uses
CB-7921220 is an adenylate cyclase inhibitor.
References
[1] Brand CS, et al. Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compounds. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75. DOI:10.1124/jpet.113.208157
CB-7921220 Preparation Products And Raw materials
Raw materials
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