GC376
- Product Name
- GC376
- CAS No.
- 1416992-39-6
- Chemical Name
- GC376
- Synonyms
- 376;GC376 sodium;GC376;GPC376;GC376 Sodium Bulk;GC376 (sodium salt);GC-376 sodium,GC376 sodium;3 alpha, 7 alpha-dyhydroxy-6-ethidene- cholanic acid;sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4- methylpentanamido)- 1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane- 1-;Sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate
- CBNumber
- CB43333611
- Molecular Formula
- C21H32N3NaO8S
- Formula Weight
- 509.55
- MOL File
- 1416992-39-6.mol
GC376 Property
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMF: 10 mg/ml,DMSO: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
Safety
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
N-Bromosuccinimide Price
- Product number
- BG167367
- Product name
- GC 376 sodium
- Packaging
- 25mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- BG167367
- Product name
- GC 376 sodium
- Packaging
- 50mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- BG167367
- Product name
- GC 376 sodium
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- BG167367
- Product name
- GC 376 sodium
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- BG167367
- Product name
- GC 376 sodium
- Packaging
- 500mg
- Price
- $650
- Updated
- 2021/12/16
GC376 Chemical Properties,Usage,Production
Description
GC376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.
Uses
GC 376 sodium is a potential small molecule inhibitor which may be able to reduce the viral load of SARS-CoV-2 3CLpro.
GC376 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from GC376 manufacturers
- Product
- GC376;GC-376 sodium 1416992-39-6
- Price
- US $1.00-0.00/g
- Min. Order
- 1ASSAYS
- Purity
- 98%+
- Supply Ability
- 10kgs
- Release date
- 2021-05-21
- Product
- GC376 1416992-39-6
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000t/year
- Release date
- 2023-09-08
- Product
- GC376 sodium 1416992-39-6
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2019-12-30