ChemicalBook > CAS DataBase List > PD0176078
PD0176078
- Product Name
- PD0176078
- CAS No.
- 248922-46-5
- Chemical Name
- PD0176078
- Synonyms
- PD0176078;PD0176078, 10 mM in DMSO;(2S)-N-[4,4-Bis(4-fluorophenyl)butyl]-4-methyl-2-(methylamino)pentanamide;Pentanamide, N-[4,4-bis(4-fluorophenyl)butyl]-4-methyl-2-(methylamino)-, (2S)-
- CBNumber
- CB43339688
- Molecular Formula
- C23H30F2N2O
- Formula Weight
- 388.49
- MOL File
- 248922-46-5.mol
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PD0176078 Property
- Boiling point:
- 541.0±50.0 °C(Predicted)
- Density
- 1.083±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 15.57±0.46(Predicted)
- color
- Off-white to light yellow
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PD0176078 Chemical Properties,Usage,Production
Uses
PD0176078 is a newly found N-type Calcium channel blocker.
IC 50
N-type calcium channel
References
[1] Yamamoto T, et al. Discovery, structure-activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity. Bioorg Med Chem. 2006 Aug 1;14(15):5333-9. DOI:10.1016/j.bmc.2006.03.040
[2] TakashiYamamoto, et al. Discovery, structure-activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity. Bioorg Med Chem. 2006 Aug 1;14(15):5333-9.
PD0176078 Preparation Products And Raw materials
Raw materials
Preparation Products
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