5-CHLOROBENZOTHIOPHENE

Product Name: 5-CHLOROBENZOTHIOPHENE
CAS No.: 20532-33-6
Chemical Name: 5-CHLOROBENZOTHIOPHENE
Synonyms: 5-Chlorothionaphthene;5-CHLOROBENZOTHIOPHENE;5-chloro-1-benzothiophene;6-chlorobenzo[b]thiophene;5-chlorine Benzothiophene;5-Chlorobenzo[b]thiophene;5-Chlorobenzothiophene ,98%;Benzo[b]thiophene, 5-chloro-;5-Chlorobenzothiophene in isooctane;5-chlorine thiofuran-2-carboxylic acid
CBNumber: CB4334138
Molecular Formula: C8H5ClS
Formula Weight: 168.64
MOL File: 20532-33-6.mol

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5-CHLOROBENZOTHIOPHENE Property

Boiling point:: 85 °C(Press: 4 Torr)
Density: 1.349±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Solid
color: Off-white
Water Solubility: Slightly soluble in water.

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-37/39
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: C381680
Product name: 5-Chlorobenzothiophene
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 072761
Product name: 5-Chlorobenzothiophene
Purity: 95+%
Packaging: 1g
Price: $25
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK227456
Product name: 5-Chlorobenzothiophene
Packaging: 500mg
Price: $30
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK227456
Product name: 5-Chlorobenzothiophene
Packaging: 1g
Price: $49
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC139709
Product name: 5-Chlorobenzothiophene
Packaging: 5G
Price: $90
Updated: 2021/12/16

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5-CHLOROBENZOTHIOPHENE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

5-Chlorobenzo[b]thiophene is used as pharmaceutical intermediate.

Synthesis

50548-46-4

20532-33-6

To a 25 mL round-bottomed flask was added (4-chlorophenyl)(2,2-diethoxyethyl)thiane (500 mg, 1.92 mmol) and chlorobenzene (2 mL). The resulting mixture was added dropwise to a boiling solution of chlorobenzene (5 mL) in polyphosphoric acid (1 g) over 5 min. After completion of the reaction, the mixture was slowly poured into ice water (25 mL) and extracted three times with ethyl acetate (25 mL). The organic phases were combined, washed with saturated saline (50 mL) and dried over anhydrous sodium sulfate. The organic phases were concentrated under reduced pressure, and the resulting crude product was purified by silica gel column chromatography, using petroleum ether as eluent, to give 5-chlorobenzothiophene (290 mg, 90% yield) as an off-white solid.

References

[1] Patent: US2008/21026, 2008, A1. Location in patent: Page/Page column 17; 27
[2] Patent: CN103896967, 2016, B. Location in patent: Paragraph 0048; 0052-0054
[3] Journal of Organic Chemistry, 1995, vol. 60, # 7, p. 1936 - 1938
[4] Phosphorus, Sulfur and Silicon and the Related Elements, 1994, vol. 96, # 1-4, p. 441 - 444
[5] Bioorganic and medicinal chemistry, 2004, vol. 12, # 9, p. 2251 - 2273

5-CHLOROBENZOTHIOPHENE Preparation Products And Raw materials

Raw materials

Toluene Sodium 4-Chlorothiophenol Polyphosphoric acid Bromoacetaldehyde dimethyl acetal Chlorobenzene Methanol

Preparation Products

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5-CHLOROBENZOTHIOPHENE Suppliers

China 102 Germany 2 India 1 Ukraine 1 United Kingdom 5 United States 16 Global 127

J & K SCIENTIFIC LTD.

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Advantage: 76

Alfa Aesar

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Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
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Energy Chemical

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Nanjing Habo Medical Technology Co., Ltd.

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Shanghai Longsheng chemical Co.,Ltd.

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Chembon Pharmaceutical Co., Ltd.

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Shandong Xiya Chemical Co., Ltd

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View Lastest Price from 5-CHLOROBENZOTHIOPHENE manufacturers

Career Henan Chemical Co

Product: 5-CHLOROBENZOTHIOPHENE 20532-33-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

20532-33-6, 5-CHLOROBENZOTHIOPHENERelated Search:

METHYL 5-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLATE 5-CHLORO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID 3-(BROMOMETHYL)-5-CHLOROBENZOTHIOPHENE 5-CHLORO-3-METHYLBENZO[B]THIOPHENE-2-SULFONYL CHLORIDE [(5-CHLOROBENZO[B]THIOPHEN-3-YL)METHYL](TRIPHENYL)PHOSPHONIUM BROMIDE 2-BROMO-1-(5-CHLORO-3-METHYLBENZO[B]THIOPHEN-2-YL)ETHAN-1-ONE 5-CHLOROBENZOTHIOPHENE-3-METHYLAMINE 5-CHLORO-3-METHYLBENZO[B]THIOPHENE-2-SULFONAMIDE 2-ACETYL-5-CHLORO-3-METHYLTHIANAPHTHENE 5-Chlorobenzothiophene-3-acetonitrile,2-(5-CHLOROBENZOTHIOPHENE-3-YL)ACETONITRILE 5-CHLORO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID 2-BROMO-5-CHLORO-3-METHYLBENZO[B]THIOPHENE 2-(5-CHLORO-3-METHYLBENZO[B]THIOPHEN-2-YL)ACETIC ACID 5-CHLORO-3-METHYLBENZO[B]THIOPHENE 5-CHLOROBENZOTHIOPHENE-3-ACETIC ACID,2-(5-CHLOROBENZOTHIOPHENE-3-YL)ACETIC ACID 5-CHLOROBENZOTHIOPHENE 7-CHLORO-3-METHYLBENZO[B]THIOPHENE METHYL 3-CHLOROBENZO[B]THIOPHENE-2-CARBOXYLATE

5-CHLOROBENZOTHIOPHENE

5-Chlorobenzo[b]thiophene

5-chlorine Benzothiophene

5-Chlorobenzothiophene ,98%

5-Chlorothionaphthene

6-chlorobenzo[b]thiophene

5-chloro-1-benzothiophene

5-chlorine thiofuran-2-carboxylic acid

Benzo[b]thiophene, 5-chloro-

5-CHLOROBENZOTHIOPHENE ISO 9001：2015 REACH

5-Chlorobenzothiophene in isooctane

20532-33-6

C8H5ClS