LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER

Product Name: LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER
CAS No.: 14565-47-0
Chemical Name: LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER
Synonyms: LAURIC ACID-OSU;DODECANOIC ACID-OSU;SUCCINIMIDYL LAURATE;N-LAUROYLOXYSUCCINIMIDE;N-SUCCINIMIDYL DODECANOATE;LAURIC ACID N-HYDROXYSUCCINIMIDE EST;2,5-Dioxopyrrolidin-1-Yl Dodecanoate;LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER;DODECANOIC ACID-N-HYDROXYSUCCINIMIDE ESTER;2,5-Pyrrolidinedione, 1-[(1-oxododecyl)oxy]-
CBNumber: CB4335074
Molecular Formula: C16H27NO4
Formula Weight: 297.39
MOL File: 14565-47-0.mol

More

Less

LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER Property

Melting point:: 76-77 °C
Boiling point:: 392.3±25.0 °C(Predicted)
Density: 1.07±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
InChI: InChI=1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-10-11-16(20)21-17-14(18)12-13-15(17)19/h2-13H2,1H3
InChIKey: LRKGVVJOUNKTGG-UHFFFAOYSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCCCCCCCCCC

More

Less

Safety

WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L3900
Product name: Lauric acid N-hydroxysuccinimide ester
Purity: ≥98% (TLC)
Packaging: 5g
Price: $412
Updated: 2022/05/15

TRC

Product number: D495508
Product name: 2,5-Dioxopyrrolidin-1-yldodecanoate
Packaging: 100mg
Price: $70
Updated: 2021/12/16

TRC

Product number: D495508
Product name: 2,5-Dioxopyrrolidin-1-yldodecanoate
Packaging: 500mg
Price: $220
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0014464
Product name: LAURIC ACID N-HYDROXYSUCCINIMIDE ESTER
Purity: 95.00%
Packaging: 5G
Price: $1115.12
Updated: 2021/12/16

Crysdot

Product number: CD11253586
Product name: 2,5-Dioxopyrrolidin-1-yldodecanoate
Purity: 97%
Packaging: 10g
Price: $569
Updated: 2021/12/16

More

Less

LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER Chemical Properties,Usage,Production

Uses

(2,5-Dioxopyrrolidin-1-yl) dodecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Biochem/physiol Actions

Lauric acid N-hydroxysuccinimide ester may be used for the synthesis of N-acylamino acids and lipidization of polypeptides or other applications that use N-hydroxysuccinimide ester conjugation chemistry.

Synthesis

143-07-7

6066-82-6

14565-47-0

General procedure: lauric acid (12.0 g, 60 mmol) was dissolved in anhydrous ethyl acetate (100 mL), followed by slow addition of this solution to a solution of anhydrous ethyl acetate (300 mL) containing N-hydroxysuccinimide (NHS) (6.9 g, 60 mmol) and N,N'-dicyclohexylcarbodiimide (DCC) (12.4 g, 60 mmol). . The reaction mixture was stirred overnight at room temperature. After completion of the reaction, the by-product dicyclohexylurea (DCU) was removed by filtration. The filtrate was concentrated under reduced pressure to afford the white crystalline product 2,5-dioxopyrrolidin-1-yl dodecanoate (17.4 g, 95% yield). For further purification, the product was recrystallized with ethanol to give a final pure product of 16.6g.

References

[1] Journal of the American Chemical Society, 2015, vol. 137, # 24, p. 7692 - 7705
[2] Journal of the American Chemical Society, 2003, vol. 125, # 40, p. 12110 - 12111
[3] RSC Advances, 2015, vol. 5, # 81, p. 66339 - 66354
[4] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 6, p. 1763 - 1767
[5] Synthetic Communications, 2009, vol. 39, # 24, p. 4467 - 4472

LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER Suppliers

China 41 Germany 1 Switzerland 1 United Kingdom 1 United States 9 Global 53

Suzhouhongxiong

Tel: 18051745768
Email: Suzhouhongxiong@163.com
Country: China
ProdList: 70
Advantage: 58

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd

Tel: 18210788515
Fax: 18210788515
Email: zhuzixin999@163.c0m
Country: China
ProdList: 2998
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Yantai ShengKailun Chemical Technology Co., Ltd.

Tel: 13356901049
Fax: QQ：1025383091
Email: 3119594100@qq.com
Country: China
ProdList: 7964
Advantage: 55

More

Less

View Lastest Price from LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Lauric acid N-hydroxy-succinimide ester 14565-47-0
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2019-12-27

14565-47-0, LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTERRelated Search:

Sodium nitrite 3-KETOPALMITIC ACID NHS ESTER PENTADECANOIC ACID N-HYDROXYSUCCINIMIDE ESTER N-SUCCINIMIDYLOXYCARBONYLPENTADECYL METHANETHIOSULFONATE Disuccinimidyl dodecanoate N-SUCCINIMIDYL PALMITATE Stearic acid-N-hydroxysuccinimide ester 12-(1,2:3,4-DIISOPROPYLIDEN-6-DEOXY-6-MERCAPTOALPHA-D-GALACTO-PYRANOS-6-YL)-DODECANOIC-ACID-HYDROXYSUCCINIMIDESTER Succinimidyl Myristate LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER N-SUCCINIMIDYLOXYCARBONYLUNDECYL METHANETHIOSULFONATE SUCCINIMIDYL NERVONATE

2,5-Pyrrolidinedione, 1-[(1-oxododecyl)oxy]-

2,5-Dioxopyrrolidin-1-Yl Dodecanoate

LAURIC ACID N-HYDROXYSUCCINIMIDE EST

SUCCINIMIDYL LAURATE

N-LAUROYLOXYSUCCINIMIDE

N-SUCCINIMIDYL DODECANOATE

Lauric acid-N-hydroxysuccinimide ester N-Succinimidyl dodecanoate

Lauric acid N-hydroxysuccinimide ester,Succinimidyl laurate

DODECANOIC ACID-N-HYDROXYSUCCINIMIDE ESTER

DODECANOIC ACID-OSU

LAURIC ACID-OSU

LAURIC ACID N-HYDROXY-SUCCINIMIDE ESTER

Dodecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester

14565-47-0