NSC232003

Product Name: NSC232003
CAS No.: 1905453-18-0
Chemical Name: NSC232003
Synonyms: NSC232003;5-(1-(Hydroxyamino)ethylidene)pyrimidine-2,4(3H,5H)-dione;2,4(3H,5H)-Pyrimidinedione, 5-[1-(hydroxyamino)ethylidene]-;E2 conjugating enzyme,Ubiquitin activating enzyme,Inhibitor,NSC 232003,inhibit,E1 activating enzyme,Ubiquitin conjugating enzyme,E1/E2/E3 Enzyme,E3 ligating enzyme,NSC232003,Ubiquitin ligase,NSC-232003
CBNumber: CB43356168
Molecular Formula: C6H7N3O3
Formula Weight: 169.14
MOL File: 1905453-18-0.mol

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NSC232003 Property

Density: 1.60±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Water : 17 mg/mL (100.51 mM);DMSO : < 1 mg/mL (insoluble or slightly soluble)
form: Solid
pka: 9.32±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7657
Product name: NSC232003
Purity: 98.66%
Packaging: 1mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-7657
Product name: NSC232003
Purity: 98.66%
Packaging: 5mg
Price: $540
Updated: 2021/12/16

ChemScene

Product number: CS-7657
Product name: NSC232003
Purity: 98.66%
Packaging: 10mg
Price: $900
Updated: 2021/12/16

ChemScene

Product number: CS-7657
Product name: NSC232003
Purity: 98.66%
Packaging: 50mg
Price: $2700
Updated: 2021/12/16

ChemScene

Product number: CS-7657
Product name: NSC232003
Purity: 98.66%
Packaging: 100mg
Price: $4020
Updated: 2021/12/16

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NSC232003 Chemical Properties,Usage,Production

Uses

NSC232003 is a highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level.

References

[1] Myrianthopoulos V, et al. Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation. Eur J Med Chem. 2016 May 23;114:390-6. DOI:10.1016/j.ejmech.2016.02.043

NSC232003 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC232003 Suppliers

China 32 United States 5 USA 1 Global 38

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1905453-18-0, NSC232003Related Search:

D18

NSC232003

5-(1-(Hydroxyamino)ethylidene)pyrimidine-2,4(3H,5H)-dione

E2 conjugating enzyme,Ubiquitin activating enzyme,Inhibitor,NSC 232003,inhibit,E1 activating enzyme,Ubiquitin conjugating enzyme,E1/E2/E3 Enzyme,E3 ligating enzyme,NSC232003,Ubiquitin ligase,NSC-232003

2,4(3H,5H)-Pyrimidinedione, 5-[1-(hydroxyamino)ethylidene]-

1905453-18-0