ChemicalBook > CAS DataBase List > {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

Product Name
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester
CAS No.
1807521-06-7
Chemical Name
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester
Synonyms
Ph-Bis(C1-N-(C2-NH-Boc)2);{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester;tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate;10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester
CBNumber
CB43363807
Molecular Formula
C36H64N6O8
Formula Weight
708.93
MOL File
1807521-06-7.mol
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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Property

Boiling point:
775.5±60.0 °C(Predicted)
Density 
1.093±0.06 g/cm3(Predicted)
pka
11.79±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22351
Product name
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Purity
96%
Packaging
100mg
Price
$350
Updated
2021/12/16
Apolloscientific
Product number
OR323158
Product name
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Packaging
100mg
Price
$731
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-1-3H
Product name
tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate
Packaging
100mg
Price
$807
Updated
2021/12/16
BroadPharm
Product number
BP-22351
Product name
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Purity
96%
Packaging
500mg
Price
$980
Updated
2021/12/16
BroadPharm
Product number
BP-22351
Product name
{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester
Purity
96%
Packaging
1g
Price
$1470
Updated
2021/12/16
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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Chemical Properties,Usage,Production

Biological Activity

Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Suppliers

China 7 United Kingdom 1 United States 3 Global 11
Jinan elephant international trading co., LTD
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13006575422@163.com
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China
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Zhengzhou Akem Chemical Co., Ltd
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13303867194
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 15801484223;
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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0431-80514535 19917294565
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Jilin Chinese Academy of Sciences-yanshen Technology
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18143011203
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Jilin Chinese Academy of Sciences-yanshen Technology
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+undefined18143011203
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info@chemextension.com
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China
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42056
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1807521-06-7, {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl esterRelated Search:


  • {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester
  • tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate
  • Ph-Bis(C1-N-(C2-NH-Boc)2)
  • 10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester
  • 1807521-06-7