t-Boc-N-Amido-PEG2-Ms

Product Name: t-Boc-N-Amido-PEG2-Ms
CAS No.: 302331-20-0
Chemical Name: t-Boc-N-Amido-PEG2-Ms
Synonyms: Boc-N-PEG2-Ms;Boc-NH-PEG2-Ms;Boc-N-PEG2-Oms;t-Boc-N-Amido-PEG2-Ms;2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl methanesulfonate;5,8-Dioxa-9-thia-2-azadecanoic acid, 1,1-dimethylethyl ester, 9,9-dioxide
CBNumber: CB43364011
Molecular Formula: C10H21NO6S
Formula Weight: 283.34
MOL File: 302331-20-0.mol

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t-Boc-N-Amido-PEG2-Ms Property

Boiling point:: 439.8±30.0 °C(Predicted)
Density: 1.182±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light
form: Liquid
pka: 12.18±0.46(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23290
Product name: t-Boc-N-Amido-PEG2-Ms
Purity: 98%
Packaging: 1g
Price: $480
Updated: 2021/12/16

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t-Boc-N-Amido-PEG2-Ms Chemical Properties,Usage,Production

Description

t-Boc-N-Amido-PEG2-Ms is a PEG linker that contains a Boc protecting group and a mesyl group. The t-Boc group can be removed under acidic conditions. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains increase the water solubility properties of the compound.

Uses

Boc-N-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-Amido-PEG2-Ms Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-Amido-PEG2-Ms Suppliers

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View Lastest Price from t-Boc-N-Amido-PEG2-Ms manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Boc-NH-PEG2-Ms 302331-20-0
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-25

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t-Boc-N-Amido-PEG2-Ms

Boc-N-PEG2-Ms

Boc-NH-PEG2-Ms

2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl methanesulfonate

Boc-N-PEG2-Oms

5,8-Dioxa-9-thia-2-azadecanoic acid, 1,1-dimethylethyl ester, 9,9-dioxide

302331-20-0