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t-Butoxycarbonyl-PEG2-sulfonic acid

Product Name
t-Butoxycarbonyl-PEG2-sulfonic acid
CAS No.
1817735-40-2
Chemical Name
t-Butoxycarbonyl-PEG2-sulfonic acid
Synonyms
Boc-PEG2-sulfonic acid;t-Butoxycarbonyl-PEG2-sulfonic acid;Propanoic acid, 3-[2-(2-sulfoethoxy)ethoxy]-, 1-(1,1-dimethylethyl) ester
CBNumber
CB43364026
Molecular Formula
C11H22O7S
Formula Weight
298.35
MOL File
1817735-40-2.mol
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t-Butoxycarbonyl-PEG2-sulfonic acid Property

Density 
1.218±0.06 g/cm3(Predicted)
pka
1.34±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22887
Product name
t-Butoxycarbonyl-PEG2-sulfonicacid
Purity
98%
Packaging
100mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-22887
Product name
t-Butoxycarbonyl-PEG2-sulfonicacid
Purity
98%
Packaging
250mg
Price
$480
Updated
2021/12/16
BroadPharm
Product number
BP-22887
Product name
t-Butoxycarbonyl-PEG2-sulfonicacid
Purity
98%
Packaging
500mg
Price
$730
Updated
2021/12/16
BroadPharm
Product number
BP-22887
Product name
t-Butoxycarbonyl-PEG2-sulfonicacid
Purity
98%
Packaging
1g
Price
$1200
Updated
2021/12/16
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t-Butoxycarbonyl-PEG2-sulfonic acid Chemical Properties,Usage,Production

Description

t-Butoxycarbonyl-PEG2-sulfonic acid is a PEG linker containing a t-Boc protecting group and sulfonic acid moiety. The t-Boc protecting group can be removed under acidic conditions. The sulfonic acid can undergo esterification, halogenation and displacement reactions. The hydrophilic PEG linkers increase the water solubility of a compound in aqueous conditions.

Uses

Boc-PEG2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Butoxycarbonyl-PEG2-sulfonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Butoxycarbonyl-PEG2-sulfonic acid Suppliers

Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
13892832556
Email
2440688701@qq.com
Country
China
ProdList
1994
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9681
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
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58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
et@chemextension.com
Country
China
ProdList
5061
Advantage
58
Shanxi Nuocheng Biotechnology Co., Ltd
Tel
17835231871
Email
572710841@qq.com
Country
China
ProdList
485
Advantage
58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
32034
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29423
Advantage
58
Taizhou Chuanxu Pharmaceutical Technology Co., Ltd.
Tel
13000000000
Email
974144639@qq.com
Country
China
ProdList
9979
Advantage
58

1817735-40-2, t-Butoxycarbonyl-PEG2-sulfonic acidRelated Search:


  • t-Butoxycarbonyl-PEG2-sulfonic acid
  • Boc-PEG2-sulfonic acid
  • Propanoic acid, 3-[2-(2-sulfoethoxy)ethoxy]-, 1-(1,1-dimethylethyl) ester
  • 1817735-40-2
  • C11H22O7S