ChemicalBook > CAS DataBase List > PD1 Inhbitor, Aurigene Cmpd 16
PD1 Inhbitor, Aurigene Cmpd 16
- Product Name
- PD1 Inhbitor, Aurigene Cmpd 16
- CAS No.
- 2005454-12-4
- Chemical Name
- PD1 Inhbitor, Aurigene Cmpd 16
- Synonyms
- PD-1 Inhibitor 16;PD1 Inhbitor, Aurigene Cmpd 16;PD1 PDL1 IN 1,PD-1-PDL1-IN 1,PD1PDL1IN 1;PD-1 INHIBITOR 16 (AURIGENE COMPOUND 16);L-Threonine, N-[[[(1S)-3-amino-3-oxo-1-[3-(1-piperazinyl)-1,2,4-oxadiazol-5-yl]propyl]amino]carbonyl]-
- CBNumber
- CB43364617
- Molecular Formula
- C14H23N7O6
- Formula Weight
- 385.38
- MOL File
- 2005454-12-4.mol
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PD1 Inhbitor, Aurigene Cmpd 16 Property
- Density
- 1.437±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 3.43±0.10(Predicted)
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PD1 Inhbitor, Aurigene Cmpd 16 Chemical Properties,Usage,Production
Description
PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1].
PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1].
Uses
PD1-PDL1-IN 1 (compound 16) is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1].
References
[1] Pottayil Govindan Nair Sasikumar , et al. 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators. WO2016142886A2.
PD1 Inhbitor, Aurigene Cmpd 16 Preparation Products And Raw materials
Raw materials
Preparation Products
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PD1 Inhbitor, Aurigene Cmpd 16 Suppliers
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