ChemicalBook > CAS DataBase List > 3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

Product Name
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS No.
133847-06-0
Chemical Name
3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Synonyms
YU142670;YU142670 >=98% (HPLC);1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 3-(4-pyridinyl)-;3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CBNumber
CB43365159
Molecular Formula
C8H5N5S
Formula Weight
203.22
MOL File
133847-06-0.mol
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3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Property

storage temp. 
2-8°C
solubility 
DMSO: 2mg/mL, clear (warmed)
form 
powder
color 
white to light brown
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Hazard and Precautionary Statements (GHS)

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3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Chemical Properties,Usage,Production

Description

YU142670 is a novel selective inhibitor against OCRL1/INPP5F and OCRL2/INPP5B by targeting OCRL catalytic domain.

Uses

YU142670 is an inhibitor of OCRL/INPP5B with IC50 values of 0.71 μM and 1.78 μM respectively[1].

References

[1] Mills SJ, et al. Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family. Biochemistry. 2016 Mar 8;55(9):1384-97. DOI:10.1021/acs.biochem.5b00838

3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Suppliers

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Guangzhou Isun Pharmaceutical Co., Ltd
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133847-06-0, 3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleRelated Search:


  • 3-(4-pyridinyl)-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole 3-(Pyridin-4-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
  • YU142670
  • 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 3-(4-pyridinyl)-
  • YU142670 >=98% (HPLC)
  • 133847-06-0