ChemicalBook > CAS DataBase List > ARQ-531

ARQ-531

Product Name: ARQ-531
CAS No.: 2095393-15-8
Chemical Name: ARQ-531
Synonyms: ARQ-531;ARQ 531, 10 mM in DMSO;Nemtabrutinib (ARQ-531);Nemtabrutinib (ARQ 531) ，S8711;Btk,MK1026,ARQ-531,MK 1026,Inhibitor,inhibit,ARQ 531,Bruton tyrosine kinase,MK-1026,ARQ531;(2-chloro-4-phenoxyphenyl)-[4-[[(3R,6S)-6-(hydroxymethyl)oxan-3-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone;D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-;D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy- (ACI);(2-chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone;(2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone
CBNumber: CB43384749
Molecular Formula: C25 H23 Cl N4 O4
Formula Weight: 0
MOL File: 2095393-15-8.mol

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ARQ-531 Property

storage temp.: Store at -20°C
solubility: DMSO : ≥ 50 mg/mL (104.40 mM)
form: Solid
color: White to off-white
InChIKey: JSFCZQSJQXFJDS-OYFFHAMFNA-N
SMILES: C(C1=CC=C(OC2=CC=CC=C2)C=C1Cl)(C1C2C(N[C@@H]3CC[C@@H](CO)OC3)=NC=NC=2NC=1)=O |&1:19,22,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0044154
Product name: ARQ531
Purity: 99.24%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0044154
Product name: ARQ531
Purity: 99.24%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0044154
Product name: ARQ531
Purity: 99.24%
Packaging: 25mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0044154
Product name: ARQ531
Purity: 99.24%
Packaging: 50mg
Price: $950
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573108
Product name: ARQ-531
Purity: >98%
Packaging: 100mg
Price: $1356.6
Updated: 2021/12/16

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ARQ-531 Chemical Properties,Usage,Production

Uses

ARQ 531 is a reversible non-covalent inhibitor of Bruton’s Tyrosine Kinase (BTK),with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. It shows strong target inhibition in TMD8 cell line.

ARQ-531 Preparation Products And Raw materials

Raw materials

Preparation Products

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ARQ-531 Suppliers

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2095393-15-8, ARQ-531Related Search:

ARQ-531

(2-chloro-4-phenoxyphenyl)-[4-[[(3R,6S)-6-(hydroxymethyl)oxan-3-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]methanone

1,?5-?Anhydro-?2-?[[5-?(2-?chloro-?4-?phenoxybenzoyl)?-?7H-?pyrrolo[2,?3-?d]?pyrimidin-?4-?yl]?amino]?-?2,?3,?4-?trideoxy-?D-?erythro-?hexitol

D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-

(2-Chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone

D-erythro-Hexitol, 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy- (ACI)

(2-chloro-4-phenoxyphenyl)(4-(((3R,6S)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone

Nemtabrutinib (ARQ-531)

Btk,MK1026,ARQ-531,MK 1026,Inhibitor,inhibit,ARQ 531,Bruton tyrosine kinase,MK-1026,ARQ531

ARQ 531, 10 mM in DMSO

Nemtabrutinib (ARQ 531) ，S8711

2095393-15-8

ARQ-531