Neoseptin 3
- Product Name
- Neoseptin 3
- CAS No.
- 1622863-21-1
- Chemical Name
- Neoseptin 3
- Synonyms
- Neoseptin 3;Neoseptin-3 >=98% (HPLC);tert-butyl (2S)-2-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-4-phenylbutanoate;Benzenebutanoic acid, α-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-, 1,1-dimethylethyl ester, (αS)-
- CBNumber
- CB43386501
- Molecular Formula
- C29H34N2O4
- Formula Weight
- 474.6
- MOL File
- 1622863-21-1.mol
Neoseptin 3 Property
- Boiling point:
- 663.9±55.0 °C(Predicted)
- Density
- 1.174±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: ≥ 100 mg/mL (210.71 mM)
- form
- Solid
- pka
- 10.05±0.15(Predicted)
- color
- White to off-white
- optical activity
- [α]/D 37 to 45°, c =0.1 in chloroform
N-Bromosuccinimide Price
- Product number
- CS-0035376
- Product name
- Neoseptin3
- Purity
- >98.0%
- Packaging
- 5mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- CS-0035376
- Product name
- Neoseptin3
- Purity
- >98.0%
- Packaging
- 10mg
- Price
- $340
- Updated
- 2021/12/16
- Product number
- CS-0035376
- Product name
- Neoseptin3
- Purity
- >98.0%
- Packaging
- 25mg
- Price
- $720
- Updated
- 2021/12/16
Neoseptin 3 Chemical Properties,Usage,Production
Biological Activity
Neoseptin-3 is a highly efficacious and specific agonist of the mouse TLR4 (mTLR4)/myeloid differentiation factor 2 (MD-2) complex. Neoseptin-3 binds to MD2, changes the conformation of MD-2 and facilitates active TLR4/MD-2 dimer formation. Neoseptin-3 exhibits no structural similarity to lipid A. ', 'Neoseptin-3 stimulates the activity of mouse TLR4 (mTLR4)/myeloid differentiation factor 2 (mTLR) independently of CD14 (cluster of differentiation 14). This activated mTLR4/ mTLR promotes canonical myeloid differentiation primary response gene 88 (MyD88) and toll-interleukin(IL) 1 receptor (TIR) domain-containing adaptor inducing interferon (IFN)-β (TRIF)-dependent signaling. In addition, neoseptin-3 also stimulates tumor necrosis factor α (TNF-α), IL-6 and IFNβ production in a dose-dependent manner.
Neoseptin 3 Preparation Products And Raw materials
Raw materials
Preparation Products
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