BPV(HOPIC)

Product Name: BPV(HOPIC)
CAS No.: 722494-26-0
Chemical Name: BPV(HOPIC)
Synonyms: BPV(HOPIC);K2[VO(O2)2C6H4NO3];Bisperoxovanadium(HOpic);BpV(HOpic), 10 mM in DMSO;bpV(HOpic) (potassium salt);bpV(HOpic), PTP and PTEN inhibitor;bpV(HOpic) (potassium salt, technical grade);DIPOTASSIUM BISPEROXO(5-HYDROXYPYRIDINE-2-CARBOXYL)OXOVANADATE (V);MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),signalling
CBNumber: CB4343644
Molecular Formula: C6H4K2NO8V
Formula Weight: 347.24
MOL File: Mol file

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BPV(HOPIC) Property

storage temp.: -20°C
solubility: H2O: soluble20mg/mL, clear
form: powder
color: faint yellow to dark yellow
Water Solubility: water: 4mg/mL

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0884
Product name: bpV(HOpic)
Purity: ≥90% V basis
Packaging: 5mg
Price: $101.65
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0884
Product name: bpV(HOpic)
Purity: ≥90% V basis
Packaging: 25mg
Price: $431
Updated: 2025/07/31

Sigma-Aldrich

Product number: 203701
Product name: bpV(HOpic)
Purity: A potent phosphotyrosine phosphatase inhibitor.
Packaging: 5MG
Price: $176
Updated: 2025/07/31

Cayman Chemical

Product number: 14433
Product name: bpV(HOpic) (potassium salt)
Purity: ≥95%
Packaging: 5mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 14433
Product name: bpV(HOpic) (potassium salt)
Purity: ≥95%
Packaging: 25mg
Price: $288
Updated: 2024/03/01

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BPV(HOPIC) Chemical Properties,Usage,Production

Uses

bpV(HOpic) has been used in pharmacological perturbation of cell migration related signaling pathway.

Biochem/physiol Actions

bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury.

in vivo

BpV(HOpic) (0.05 mg/kg; i.p.) at reperfusion ameliorates liver ischemia/reperfusion (I/R) injury in vivo^[6].
BpV(HOpic) (200 μg/kg; i.p.) exacerbates renal dysfunction and promotes tubular damage in mice with ischemia/reperfusion injury (IRI)^[7].

Animal Model:	Male Wistar rats are subjected to partial hepatic ischemia^[6]
Dosage:	0.05 mg/kg
Administration:	I.p. injections at the start of reperfusion
Result:	Ameliorated reoxygenation injury and reproduced the hepatoprotective effects obtained by adenosine A2A receptor stimulation.

Animal Model:	Male C57BL/6 mice (8-12 weeks old; 20-30 g ) are subjected to renal ischemia^[7]
Dosage:	200?μg/kg
Administration:	I.p. injections 1?h before ischemia and then administers every 6?h after ischemia for 24 hr
Result:	Raised the level of serum creatinine and blood serum urea nitrogen.

BPV(HOPIC) Preparation Products And Raw materials

Raw materials

Preparation Products

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BPV(HOPIC) Suppliers

China 81 India 1 Switzerland 1 United Kingdom 1 United States 12 Global 96

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722494-26-0, BPV(HOPIC)Related Search:

BPV(HOPIC)

DIPOTASSIUM BISPEROXO(5-HYDROXYPYRIDINE-2-CARBOXYL)OXOVANADATE (V)

Bisperoxovanadium(HOpic)

K2[VO(O2)2C6H4NO3]

bpV(HOpic) (potassium salt)

bpV(HOpic) (potassium salt, technical grade)

MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),signalling

bpV(HOpic), PTP and PTEN inhibitor

BpV(HOpic), 10 mM in DMSO

722494-26-0

C6H4NO8V2K