BPV(HOPIC)
- Product Name
- BPV(HOPIC)
- CAS No.
- 722494-26-0
- Chemical Name
- BPV(HOPIC)
- Synonyms
- BPV(HOPIC);K2[VO(O2)2C6H4NO3];Bisperoxovanadium(HOpic);bpV(HOpic) (potassium salt);bpV(HOpic) (potassium salt, technical grade);DIPOTASSIUM BISPEROXO(5-HYDROXYPYRIDINE-2-CARBOXYL)OXOVANADATE (V);MAPK/ERK,Phosphatase and tensin homolog,Inhibitor,PTEN,MMAC1,inhibit,PI3K/AKT,BpV(HOpic),signalling
- CBNumber
- CB4343644
- Molecular Formula
- C6H4K2NO8V
- Formula Weight
- 347.24
- MOL File
- Mol file
BPV(HOPIC) Property
- storage temp.
- -20°C
- solubility
- H2O: soluble20mg/mL, clear
- form
- powder
- color
- faint yellow to dark yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SML0884
- Product name
- bpV(HOpic)
- Purity
- ≥90% V basis
- Packaging
- 5mg
- Price
- $104
- Updated
- 2024/03/01
- Product number
- SML0884
- Product name
- bpV(HOpic)
- Purity
- ≥90% V basis
- Packaging
- 25mg
- Price
- $419
- Updated
- 2024/03/01
- Product number
- 203701
- Product name
- bpV(HOpic)
- Purity
- A potent phosphotyrosine phosphatase inhibitor.
- Packaging
- 5MG
- Price
- $201
- Updated
- 2024/03/01
- Product number
- 14433
- Product name
- bpV(HOpic) (potassium salt)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $73
- Updated
- 2024/03/01
- Product number
- 14433
- Product name
- bpV(HOpic) (potassium salt)
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $288
- Updated
- 2024/03/01
BPV(HOPIC) Chemical Properties,Usage,Production
Uses
bpV(HOpic) has been used in pharmacological perturbation of cell migration related signaling pathway.
Biochem/physiol Actions
bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury.