ChemicalBook > CAS DataBase List > 2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE

Product Name
2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE
CAS No.
133040-77-4
Chemical Name
2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE
Synonyms
LY 225910;2-(2-(5-BroMo-1H-indol-3-yl)ethyl)-3-(3-isopropoxyphenyl)quinazolin-4(3H)-one;2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one;2-(2-(5-Bromo-(1H)-indol-3-yl)ethyl)-3-(3-(1-methylethoxy)phenyl)-4-(3H)-quinazoline;2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE;4(3H)-Quinazolinone, 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-
CBNumber
CB4349752
Molecular Formula
C27H24BrN3O2
Formula Weight
502.4
MOL File
133040-77-4.mol
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2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Property

Flash point:
337 - 405℃
storage temp. 
Desiccate at -20°C
solubility 
DMSO: >20mg/mL
form 
powder
color 
off-white
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Safety

Hazard Codes 
Xn
Risk Statements 
22
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L2545
Product name
LY225910
Purity
≥98% (HPLC)
Packaging
25mg
Price
$489
Updated
2024/03/01
Sigma-Aldrich
Product number
L2545
Product name
LY225910
Purity
≥98% (HPLC)
Packaging
5mg
Price
$137
Updated
2022/05/15
Tocris
Product number
1018
Product name
LY225910
Packaging
10
Price
$115
Updated
2021/12/16
Tocris
Product number
1018
Product name
LY225910
Packaging
50
Price
$479
Updated
2021/12/16
TRC
Product number
L503145
Product name
LY225910
Packaging
10mg
Price
$185
Updated
2021/12/16
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2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Chemical Properties,Usage,Production

Uses

LY 225910 is a potent CCK-BR antagonist.

Definition

ChEBI: 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-(3-propan-2-yloxyphenyl)-4-quinazolinone is a member of quinazolines.

Biological Activity

Potent CCK 2 receptor antagonist (IC 50 = 9.3 nM for inhibition of 125 I-labeled CCK-8 sulfate binding at mouse brain membranes).

storage

Desiccate at -20°C

2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

133040-77-4, 2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONERelated Search:


  • LY 225910
  • 2-[2-(5-BROMO-1H-INDOL-3-YL)ETHYL]-3-[3-(1-METHYLETHOXY)PHENYL]-4-(3H)-QUINAZOLINONE
  • 2-(2-(5-Bromo-(1H)-indol-3-yl)ethyl)-3-(3-(1-methylethoxy)phenyl)-4-(3H)-quinazoline
  • 2-(2-(5-BroMo-1H-indol-3-yl)ethyl)-3-(3-isopropoxyphenyl)quinazolin-4(3H)-one
  • 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
  • 4(3H)-Quinazolinone, 2-[2-(5-bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-
  • 133040-77-4
  • C27H24BrN3O2