CIS-ACONITIC ACID Property

Melting point:

122 °C (lit.)

Boiling point:

225.05°C (rough estimate)

Density 

1.660

refractive index 

1.5860 (estimate)

FEMA 

2010 | ACONITIC ACID

storage temp. 

-20°C

solubility 

Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

1.95(at 25℃)

color 

White to Off-White

PH

3.05(1 mM solution);2.21(10 mM solution);1.55(100 mM solution)

Odor

bland

Water Solubility 

Soluble in water, alcohol. Slightly soluble in ether.

BRN 

1725829

Stability:

Hygroscopic, Light Sensitive

LogP

-0.14

CAS DataBase Reference

585-84-2(CAS DataBase Reference)

EPA Substance Registry System

1-Propene-1,2,3-tricarboxylic acid, (1Z)- (585-84-2)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

36/38-40-36/37/38

Safety Statements 

26-36/37-36

WGK Germany 

1

F 

3

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

2917198090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H350May cause cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

CIS-ACONITIC ACID Chemical Properties,Usage,Production

Chemical Properties

WHITE TO ALMOST WHITE POWDER

Uses

cis-Aconitic acid is used as an intermediate in the production of substances pharmaceuticals. It is widely used in chemical research and as reagent. It acts as a cis-isomer of aconitic acid.

Uses

cis-Aconitic acid can be used as a standard for the determination of organic acids in plant tissues.

Uses

cis-Aconitic Acid is the cis-isomer of Aconitic Acid. The conjugate base of cis-Aconitic Acid is an intermediate in the isomerization of citrate and isocitrate in the citric acid cycle.

Definition

ChEBI: The cis-isomer of aconitic acid.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Purification Methods

Crystallise the cis-acid from water by cooling (solubility is 1g in 2mL of water at 25o). Dry it in a vacuum desiccator. [Beilstein 2 IV 2405.]