ChemicalBook > CAS DataBase List > 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
- Product Name
- 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
- CAS No.
- 36507-30-9
- Chemical Name
- 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
- Synonyms
- C07496;GP 49-023;(11-epoxide-d10);carbamazepineepoxide;carbamazepine10,11-oxide;10,11-epoxycarbamazepine;Carbamazepine Impurity 12;CARBAMAZEPINE 10,11-EPOXIDE;CarbaMazepine-10,11-epoxide-d10;Carbamazepine-10,11-epoxide solution
- CBNumber
- CB4364889
- Molecular Formula
- C15H12N2O2
- Formula Weight
- 252.27
- MOL File
- 36507-30-9.mol
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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Property
- Melting point:
- 204-206°C
- Boiling point:
- 390.2±52.0 °C(Predicted)
- Density
- 1.377±0.06 g/cm3(Predicted)
- Flash point:
- 9℃
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 13.91±0.20(Predicted)
- color
- White
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Safety
- Hazard Codes
- Xn,N,T,F
- Risk Statements
- 22-36/37/38-51/53-39/23/24/25-23/24/25-11
- Safety Statements
- 26-36-61-45-36/37-16-7
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- HQ4430000
- HazardClass
- 6.1(b)
- PackingGroup
- III
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C4206
- Product name
- Carbamazepine 10,11-epoxide
- Purity
- analytical standard
- Packaging
- 5mg
- Price
- $83.7
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C-121
- Product name
- Carbamazepine-10,11-epoxide solution
- Purity
- 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $95.5
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 93203
- Product name
- Carbamazepine 10,11-epoxide
- Purity
- analytical standard
- Packaging
- 25MG
- Price
- $619
- Updated
- 2022/05/15
Sigma-Aldrich
- Product number
- C4206
- Product name
- Carbamazepine 10,11-epoxide
- Purity
- analytical standard
- Packaging
- 25mg
- Price
- $317
- Updated
- 2024/03/01
Usbiological
- Product number
- C1080-03
- Product name
- Carbamazepine 10,11-Epoxide
- Packaging
- 25mg
- Price
- $446
- Updated
- 2021/12/16
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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A metabolite of Carbamazepine (C175840). Representative lots contained 1-2% carbamazepine by HPLC.
Uses
A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.
Uses
A metabolite of Carbamazepine. Representative lots contained 1-2% carbamazepine by HPLC
Definition
ChEBI: An epoxide and metabolite of carbamazepine.
General Description
Carbamazepine-10,11-epoxide is the primary, active metabolite in both urine and serum of carbamazepine, an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder as well as trigeminal neuralgia. Potential toxicity of the epoxide metabolite requires regular therapeutic drug monitoring by LC or LC/MS for patients taking carbamazepine.
Biochem/physiol Actions
First metabolite of carbamazepine
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE Suppliers
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36507-30-9, 1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDERelated Search:
Iminodibenzyl
CARBAMAZEPINE-13C1,15N1
CARBAMAZEPINE-D10
10,11-Dihydro-10-hydroxycarbamazepine-d3
5H-Dibenz[b,f]azepine-5-carboxamide dihydrate
rac trans-10,11-Dihydro-10,11-dihydroxy Carbamazepine
Carbamazepine
TRANS-STILBENE OXIDE
Carbamazepine-10,11-Epoxide-D2
CARBAMAZEPINE 10,11-EPOXIDE-13C,D2
1A,10B-DIHYDRO-6H-DIBENZO[B,F]OXIRENO[D]AZEPINE-6-CARBOXAMIDE
Oxcarbazepine
CARBAMAZEPINE-10,11-EPOXIDE-D10 (RINGS-D10)
10,11-DIHYDROCARBAMAZEPINE