3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE

Product Name: 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE
CAS No.: 137628-16-1
Chemical Name: 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE
Synonyms: 3-Bromo-5-chloro-2-pyridone;3-BROMO-5-CHLOROPYRIDIN-2-OL;3-Bromo-5-Chloro-2-Pyridinol;3-Bromo-5-chloropyridin-2-one;3-Bromo-5-chloro-2(1H)-pyridinone;3-bromo-5-chloropyridin-2(1H)-one;3-BROMO-5-CHLORO-2-HYDROXYPRIDINE;3-bromo-5-chloro-1H-pyridin-2-one;3-BROMO-5-CHLORO-2-HYDROXYPYRIDIN;2-hydro-5-chloro-3-bromo pyridine
CBNumber: CB4369314
Molecular Formula: C5H3BrClNO
Formula Weight: 208.44
MOL File: 137628-16-1.mol

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3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Property

Boiling point:: 277.6±40.0 °C(Predicted)
Density: 1.91±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 8.48±0.10(Predicted)
Appearance: White to off-white Solid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Apolloscientific

Product number: OR926475
Product name: 3-Bromo-5-chloropyridin-2(1h)-one
Purity: 98%
Packaging: 5g
Price: $68
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB55858
Product name: 3-Bromo-5-chloro-2-pyridone
Packaging: 1g
Price: $70
Updated: 2021/12/16

Matrix Scientific

Product number: 083832
Product name: 3-Bromo-5-chloropyridin-2-ol
Purity: 97%
Packaging: 1g
Price: $72
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB55858
Product name: 3-Bromo-5-chloro-2-pyridone
Packaging: 2g
Price: $116
Updated: 2021/12/16

Apolloscientific

Product number: OR926475
Product name: 3-Bromo-5-chloropyridin-2(1h)-one
Purity: 98%
Packaging: 10g
Price: $94
Updated: 2021/12/16

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3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Chemical Properties,Usage,Production

Synthesis

4214-79-3

137628-16-1

General procedure for the synthesis of 2-hydroxy-5-chloro-3-bromopyridine from 5-chloropyridin-2-one: 5-chloro-2-hydroxypyridine (20.1 g, 155.4 mmol) and bromine (11.9 mL) were dissolved in acetic acid (250 mL), and the reaction was stirred for 2 hours at room temperature. Upon completion of the reaction, the solvent was removed by vacuum evaporation. The residue was extracted by adding ethyl acetate (600 mL) and saturated sodium bicarbonate solution (300 mL). The organic layer was washed sequentially with saturated sodium bicarbonate solution (2 x 200 mL) and brine, followed by drying and concentration with anhydrous sodium sulfate to give the crude product. The crude product was recrystallized by hexane/ether mixed solvent to afford purified 3-bromo-5-chloro-2-hydroxypyridine (21.3 g, 66% yield), which could be used directly in the subsequent reaction.

References

[1] Patent: WO2004/72037, 2004, A1. Location in patent: Page 11
[2] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 19, p. 2777 - 2782
[3] Patent: US5861419, 1999, A
[4] Patent: US6245797, 2001, B1
[5] Patent: WO2014/141110, 2014, A2. Location in patent: Page/Page column 83; 84

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE Suppliers

China 98 Germany 1 India 10 United Kingdom 2 United States 14 Global 125

Energy Chemical

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Pure Chemistry Scientific Inc.

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Shanghai Hanhong Scientific Co.,Ltd.

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Shanghai Ennopharm Co., Ltd.

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Changzhou Wanyao Biotechnology Co., Ltd.

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Shanghai Topbiochem Technology Co., Ltd

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View Lastest Price from 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE 137628-16-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-09-26

Career Henan Chemical Co

Product: 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE 137628-16-1
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg , 5kg, 50kg
Release date: 2020-01-17

137628-16-1, 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINERelated Search:

5-CHLORO-2-HYDROXYPYRIDINE 5-CHLORO-2-HYDROXYPYRIDINE 5-Bromo-2-chloro-3-hydroxypyridine 3-Bromo-2-methoxy-5-trifluoromethylpyridine 5-BROMO-3-CHLORO-2-HYDROXYPYRIDINE 5-BROMO-3-CHLORO-2-HYDROXYPYRIDINE 2-AMINO-4-BROMO-5-CHLORO-3-HYDROXYPYRIDINE 2-Bromo-3-chloro-5-hydroxypyridine 2-Bromo-5-chloro-3-hydroxypyridine 3-Bromo-2-chloro-5-hydroxypyridine 2-AMINO-5-BROMO-4-CHLORO-3-HYDROXYPYRIDINE 3-Bromo-5-chloropyridine 3-Bromo-2-hydroxypyridine 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE 3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE

3-BROMO-5-CHLORO-2-HYDROXYPRIDINE

2-HYDROXY-3-BROMO-5-CHLOROPYRIDINE

3-BROMO-5-CHLOROPYRIDIN-2-OL

3-bromo-5-chloropyridin-2(1H)-one

3-Bromo-5-chloro-2(1H)-pyridinone

3-Bromo-5-chloro-2-pyridone

3-Bromo-5-chloropyridin-2-one

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE

3-bromo-5-chloro-1H-pyridin-2-one

2(1H)-Pyridinone, 3-bromo-5-chloro-

3-BROMO-5-CHLORO-2-HYDROXYPYRIDINE ISO 9001：2015 REACH

3-Bromo-5-Chloro-2-Pyridinol

3-BROMO-5-CHLORO-2-HYDROXYPYRIDIN

2-hydro-5-chloro-3-bromo pyridine

2-hydroxy 5-chloro 3-bromo pyridine

137628-16-1

37628-16-1

C5H3BrClNO

Pyridine Series

Pyridine

Halides

Pyridines