3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride
- Product Name
- 3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride
- CAS No.
- 1189648-08-5
- Chemical Name
- 3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride
- Synonyms
- Melitracen-d6 HCl;D6- Melitracen Hydrochloride;[2H6]- Melitracen Hydrochloride;3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride
- CBNumber
- CB43721645
- Molecular Formula
- C21H20ClD6N
- Formula Weight
- 333.927810668
- MOL File
- 1189648-08-5.mol
3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride Property
- solubility
- Chloroform (Slightly), Methanol (Sparinly), Water (Sparingly)
- form
- Solid
- color
- White to Pale Yellow
N-Bromosuccinimide Price
- Product number
- M215502
- Product name
- Melitracen-d6Hydrochloride
- Packaging
- 10mg
- Price
- $1355
- Updated
- 2021/12/16
3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride Chemical Properties,Usage,Production
Uses
Melitracen-d6 (hydrochloride) is the deuterium labeled Melitracen hydrochloride. Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space[1][2].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Xiaoqian Zhou , et al. The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis. Gastroenterol Res Pract. 2019 Feb 28;2019:3480732. DOI:10.1155/2019/3480732
[3] K Shimamoto, et al. Myriatic Effect of 9-(gamma-dimethylamino-propylidene)-10, 10-diemthyl-9, 10-dihydroanthracene Hydrochloride (Melitracen) in Mice and Rats. Acta Sch Med Univ Kioto. 1967 Jul;40(1):38-47. PMID:5591496
3-[10,10-bis(trideuteriomethyl)anthracen-9-ylidene]-N,N-dimethylpropan-1-amine:hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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