SALOR-INT L224693-1EA

Product Name: SALOR-INT L224693-1EA
CAS No.: 313380-27-7
Chemical Name: SALOR-INT L224693-1EA
Synonyms: 3-amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide;FDI 6;FDI-6 >=98% (HPLC);FOXM1 Inhibitor III;FDI-6, 10 mM in DMSO;FDI 6 - NCGC 00099374;SALOR-INT L224693-1EA;inhibit,FDI-6,Inhibitor;FOXM1 Inhibitor III (FDI-6);3-AMINO-N-(4-FLUOROPHENYL)-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
CBNumber: CB4384683
Molecular Formula: C19H11F4N3OS2
Formula Weight: 437.43
MOL File: 313380-27-7.mol

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SALOR-INT L224693-1EA Property

Boiling point:: 533.7±50.0 °C(Predicted)
Density: 1.562±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:64.34(Max Conc. mg/mL);147.09(Max Conc. mM)
form: powder (flocculent)
pka: 10.24±0.70(Predicted)
color: white to beige
InChI: 1S/C19H11F4N3OS2/c20-9-3-5-10(6-4-9)25-17(27)16-15(24)14-11(19(21,22)23)8-12(26-18(14)29-16)13-2-1-7-28-13/h1-8H,24H2,(H,25,27)
InChIKey: ZATJMMZPGVDUOM-UHFFFAOYSA-N
SMILES: NC1=C(C(NC2=CC=C(F)C=C2)=O)SC3=C1C(C(F)(F)F)=CC(C4=CC=CS4)=N3

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1392
Product name: FDI-6
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $121
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML1392
Product name: FDI-6
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $475
Updated: 2025/07/31

Sigma-Aldrich

Product number: 5.33259
Product name: FOXM1 Inhibitor III, FDI-6
Packaging: 10MG
Price: $202
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: INB0004434
Product name: 3-AMINO-N-(4-FLUOROPHENYL)-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
Purity: 95.00%
Packaging: 10MG
Price: $250.95
Updated: 2021/12/16

Axon Medchem

Product number: Axon2384
Product name: FDI6-NCGC00099374
Purity: 99%
Packaging: 50mg
Price: $324.5
Updated: 2021/12/16

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SALOR-INT L224693-1EA Chemical Properties,Usage,Production

Uses

FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation.

Biochem/physiol Actions

Forkhead domain inhibitor-6 (FDI-6) is used to treat anaemia patients because of diminished red blood production. In Hep-2 cells, FDI-6 can stimulate cell death and also helps to prevent cell proliferation, invasion and migration.

References

[1] Gormally MV, et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165. DOI:10.1038/ncomms6165

SALOR-INT L224693-1EA Preparation Products And Raw materials

Raw materials

Preparation Products

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SALOR-INT L224693-1EA Suppliers

China 44 India 1 United States 7 USA 1 Global 53

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313380-27-7, SALOR-INT L224693-1EARelated Search:

SALOR-INT L224693-1EA

3-AMINO-N-(4-FLUOROPHENYL)-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE

3-amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide

3-Amino-6-thiophen-2-yl-4-trifluoromethyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-fluoro-phenyl)-amide

FDI 6

FDI 6 - NCGC 00099374

Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)-

FDI-6 >=98% (HPLC)

FOXM1 Inhibitor III (FDI-6)

inhibit,FDI-6,Inhibitor

FOXM1 Inhibitor III

FDI-6, 10 mM in DMSO

313380-27-7