1,5,7-Triazabicyclo[4.4.0]dec-5-ene

Product Name: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene
CAS No.: 5807-14-7
Chemical Name: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene
Synonyms: TBD;1,5,7-TRIAZABICYCLO[4.4.0]DEC-5-ENE;1,5,7-Triazabicylo[4.4.0]dec-5-ene;2H-Pyrimido[1,2-a]pyrimidine, 1,3,4,6,7,8-hexahydro-;Hhpp;129727;CATALYST TBD;o[4.4.0]dec-5-ene;1,5,7-TriazabicycL;Triazabicyclodecene
CBNumber: CB4390305
Molecular Formula: C7H13N3
Formula Weight: 139.2
MOL File: 5807-14-7.mol

More

Less

1,5,7-Triazabicyclo[4.4.0]dec-5-ene Property

Melting point:: 125-130 °C(lit.)
Boiling point:: 222.3±23.0 °C(Predicted)
Density: 1.28±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: toluene: soluble1 g/15 mL
form: powder to crystal
pka: 14.47±0.20(Predicted)
color: White to Almost white
BRN: 3242
InChI: InChI=1S/C7H13N3/c1-3-8-7-9-4-2-6-10(7)5-1/h1-6H2,(H,8,9)
InChIKey: FVKFHMNJTHKMRX-UHFFFAOYSA-N
SMILES: C12=NCCCN1CCCN2
CAS DataBase Reference: 5807-14-7(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45-27
RIDADR: UN 1759 8/PG 2
WGK Germany: 3
F: 9-21-34
HazardClass: 8
PackingGroup: III
HS Code: 29335990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 358754
Product name: 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine, polymer-bound
Purity: 200-400?mesh, extent of labeling: 2.6?mmol/g loading, 2?% cross-linked with divinylbenzene
Packaging: 5G
Price: $186
Updated: 2024/03/01

Sigma-Aldrich

Product number: 345571
Product name: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene
Purity: 98%
Packaging: 5g
Price: $78.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 358754
Product name: 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine, polymer-bound
Packaging: 25g
Price: $648
Updated: 2023/06/20

TCI Chemical

Product number: T1982
Product name: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $92
Updated: 2024/03/01

TCI Chemical

Product number: T1982
Product name: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $347
Updated: 2024/03/01

More

Less

1,5,7-Triazabicyclo[4.4.0]dec-5-ene Chemical Properties,Usage,Production

Chemical Properties

Light yellow crystalline

Uses

1,5,7-Triazabicyclo[4.4.0]dec-5-ene may be used as organocatalyst for aminolysis of esters. It may be used as catalyst for direct addition of P(O)-H bonds (dialkyl phosphites and diphenyl phosphonite) across various activated alkenes. Polymer supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (PTBD) was used as a base and a reagent scavenger for the synthesis of aryl ethers from phenols and alkyl or aryl halides.

Definition

ChEBI: 3,4,6,7,8,9-hexahydro-2H-pyrimido[1,2-a]pyrimidine is a member of pyrimidines.

General Description

1,5,7-Triazabicyclo[4.4.0]dec-5-ene, a bicyclic guanidine base, has been found to be an excellent catalyst for Michael and Michael-type reactions. It forms 1:1 complex with lasalocid acid and crystal structure of the complex has been studied by X-ray diffraction, FT-IR spectroscopy and ¹H NMR.

Purification Methods

1,5,7-Triazabicyclo[4.4.0]dec-5-ene crystallises from Et2O but readily forms white crystals of the carbonate. It is a strong base (see pK, i.e. about 100 times more basic than tetramethylguanidine). The picrate has m 220.5-222o (from EtOH). It forms the 5-nitro derivative m 14.5-160o that gives a 5-nitro nitrate salt m 100-101o (from EtOH/Et2O) and a 5-nitro picrate m 144-145o (from H2O) [McKay & Kreling Can J Chem 35 1438 1957, Schwesinger Chimia 39 369 1985, Hilpert et al. J Chem Soc, Chem Commun 1401 1983, Kamfen & Eschenmoser Helv Chim Acta 72 185 1989]. [Beilstein 26 III/IV 60.]

1,5,7-Triazabicyclo[4.4.0]dec-5-ene Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1,5,7-Triazabicyclo[4.4.0]dec-5-ene Suppliers

China 206 France 1 Germany 5 India 16 Japan 1 Switzerland 1 The Netherlands 2 Ukraine 1 United Kingdom 8 United States 34 Global 275

Shanghai Jingfu Biotechnology Co., LTD

Tel: 0598-5859955 13313739955
Fax: 0598-5859955
Email: sales@jingfubio.com
Country: China
ProdList: 19
Advantage: 58

Shenzhen HwaGen Pharmaceutical Co.,Ltd

Tel: 0752-5538396 18927339850
Fax: 0752-5319394
Email: sales1@rafflespt.com
Country: China
ProdList: 216
Advantage: 58

Beri Pharma Co., Ltd.

Tel: 0756-07568699456 13427714006
Fax: +86-756-8699456
Email: sales@zhberi.com
Country: China
ProdList: 208
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 10067
Advantage: 58

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 15523000485
Email: xingcanyaoye@sina.com
Country: China
ProdList: 1686
Advantage: 58

Jinan Shangbo Biological Co., Ltd.

Tel: 0531-61320525 15866703830
Email: 495745175@qq.com
Country: China
ProdList: 6888
Advantage: 58

Shanghai Jinhuan Chemical Co.,LTD.

Tel: +86-21-52210535 +86-13162045318
Fax: +86-21-67285091
Email: sales@jinhchem.com
Country: China
ProdList: 452
Advantage: 58

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15495
Advantage: 58

EVERSHINE CHEMICAL CO., LIMITED

Tel: 17185714011 17185714011
Email: 3506894070@qq.com
Country: China
ProdList: 69
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

More

Less

View Lastest Price from 1,5,7-Triazabicyclo[4.4.0]dec-5-ene manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene 5807-14-7
Price: US $20.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 5 tons
Release date: 2023-11-06

Hebei Mojin Biotechnology Co., Ltd

Product: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene 5807-14-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-10

Hebei Guanlang Biotechnology Co., Ltd.

Product: 1,5,7-Triazabicyclo[4.4.0]dec-5-ene 5807-14-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2023-01-30

5807-14-7, 1,5,7-Triazabicyclo[4.4.0]dec-5-eneRelated Search:

Tributyltin azide Tetramethylguanidine 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO[1,2-ALPHA]PYRIMIDINE POLYMER BOUND JANDAJEL-1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2A)PYRIMIDINE 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO[1,2-A]PYRIMIDINE BOUND TO POLYSTYRENE 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO[1,2-A]PYRIMIDINE RESIN 1,5,7-Triazabicyclo[4.4.0]dec-5-ene 1-Methyl-1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine,1-Methyl-1,2,3,4,7,8-hexahydro-6H-pyrimido[1,2-a]pyrimidine AURORA KA-6614 AURORA KA-6611 AURORA KA-6613 AURORA KA-6612

LABOTEST-BB LT00847641

1,5,7-TRIAZABICYCLO[4.4.0]DEC-5-ENE

1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO[1,2-A]PYRIMIDINE

1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO[1,2-A]PYRIMIDINE, POLYMER-BOUND

TBD

2H-Pyrimido[1,2-a]pyrimidine, 1,3,4,6,7,8-hexahydro-

1,5,7-Triazabicylo[4.4.0]dec-5-ene

Silicagel, functionalized, 1,5,7-Triazabicyclo[4,4,0]dec-5-ene, 1.4

1,5,7-TRIAZABICYCLO(4.4.0)DEC-5-ENE (1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO(1,2-A)PYRIMIDINE)

Hhpp, TBD, 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine

1,2,3,4,4a,5,6,7-Octahydro-1,4a,8-triazanaphthalene

1,2,3,4,7,8-Hexahydro-6H-pyrimido[1,2-a]pyrimidine

1,2,3,5,6,7-Hexahydro-4H-1,4a,8-triazanaphthalene

1,5,7-Triazabicyclo[4.4.0]decane-5-ene

2,3,4,6,7,8-Hexahydro-1H-pyrimido[1,2-a]pyrimidine

1,5,7-Triazabicyclo(4 x 4 x 0)dec-5-ene (1,3,4,6,7,8-Hexahydro-2

1,5,7-Triazabicyclo[4.4.0]dec-5-ene,1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine, Hhpp, TBD

Hhpp

1H,2H,3H,4H,6H,7H,8H-[1,3]diazino[1,2-a]pyriMidine

1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine TBD

3,4,6,7,8,9-hexahydro-2H-pyrimido[1,2-a]pyrimidine

129727

1,5,7-TriazabicycL

o[4.4.0]dec-5-ene

3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO[1,2-A]PYRIMIDINE

1,5,7-Triazabicyclo[4.4.0]dec-5-ene 98%

StratoSpheres? PL-TBD (1,3,5-Triazabicyclodec-5-ene) resin

2H-Pyrimido[1,2-a]pyrimidine, 1,3,4,6,7,8-h

1,5,7-Triazabicyclo[4.4.0]dec-5-ene &gt

1,5,7-Triazabicyclo[4.4.0]dec-5-ene, 98%, for synthesis

1,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine

CATALYST TBD

1,5,7-Triazabicyclo[4.4.]dec-5-ene

1,5, 7-triazicycle [4.4.0] dec-5-ene

1,5,7-TRIAZABICYCLO[4.4.0]DEC-5-ENE 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine, TBD

Triazabicyclodecene

5807-14-7

5087-14-7

AMINE

Heterocyclic Building Blocks

Synthetic Reagents

Pyrimidines

Others

Organic Bases

N-Containing

Building Blocks

N-Containing

Others

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks