ChemicalBook > CAS DataBase List > N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
- Product Name
- N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
- CAS No.
- 349438-74-0
- Chemical Name
- N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
- Synonyms
- CK1-IN-3;WAY-296817;WAY296817,WAY 296817;Benzeneacetamide, 2-methoxy-N-(6-methoxy-2-benzothiazolyl)-;N-(6-Methoxybenzo[d]thiazol-2-yl)-2-(2-methoxyphenyl)acetamide;N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide
- CBNumber
- CB44020822
- Molecular Formula
- C17H16N2O3S
- Formula Weight
- 328.39
- MOL File
- 349438-74-0.mol
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N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Property
- Density
- 1.323±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 10.22±0.70(Predicted)
- form
- Solid
- color
- Gray to brown
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N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Chemical Properties,Usage,Production
Uses
CK1-IN-3 (compound 51) is a AC1 inhibitor with an IC50s 2.22 μM for CK-1δ[1][2].
in vivo
CK1-IN-3 (compound 35) (100 nM; feed) significantly extendes fly lifespan to 36.17 days[2].
IC 50
CK1δ: 2.22 μM (IC50)
References
[1] Ana MARTíNEZ GIL, et al. Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases. WO2014114825A1.
[2] Salado IG, et al. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. J Med Chem. 2014 Mar 27;57(6):2755-72. DOI:10.1021/jm500065f
N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Preparation Products And Raw materials
Raw materials
Preparation Products
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N-(6-methoxy-1,3-benzothiazol-2-yl)-2-(2-methoxyphenyl)acetamide Suppliers
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