2-BROMOINDAN
- Product Name
- 2-BROMOINDAN
- CAS No.
- 17623-96-0
- Chemical Name
- 2-BROMOINDAN
- Synonyms
- 2-BROMO-2,3-DIHYDRO-1H-INDENE;2-BROMOINDAN;β-BroMoindane;2-bromoindane;2-Bromohydroindene;2-BroMo-2,3-dihydroindene;1H-Indene, 2-broMo-2,3-dihydro-
- CBNumber
- CB4419868
- Molecular Formula
- C9H9Br
- Formula Weight
- 197.07
- MOL File
- Mol file
2-BROMOINDAN Property
- Boiling point:
- 249.2±29.0 °C(Predicted)
- Density
- 1.483±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Appearance
- Colorless to light yellow Solid-Liquid Mixture
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B684600
- Product name
- 2-Bromoindan
- Packaging
- 10g
- Price
- $1055
- Updated
- 2021/12/16
- Product number
- FB19241
- Product name
- 2-Bromoindan
- Packaging
- 10g
- Price
- $1310.4
- Updated
- 2021/12/16
- Product number
- FB19241
- Product name
- 2-Bromoindan
- Packaging
- 5G
- Price
- $720.8
- Updated
- 2021/12/16
- Product number
- FB19241
- Product name
- 2-Bromoindan
- Packaging
- 500mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 4257BB
- Product name
- 2-Bromo-2,3-dihydro-1H-indene
- Packaging
- 100mg
- Price
- $109
- Updated
- 2021/12/16
2-BROMOINDAN Chemical Properties,Usage,Production
Uses
2-BROMOINDAN is used in the synthesis of Αtipamezole, a potential PET ligand for the α2-adrenergic receptor in the brain.
Synthesis
1775-27-5
17623-96-0
General procedure for the synthesis of 2-bromo-2,3-dihydro-1H-indene from 2-bromoindanone: In a 250 mL dry three-necked flask, 22.0 g of 2-bromoindanone (bromo compound I) and 0.67 g of 5% palladium carbon catalyst were added. Subsequently, 250 mL of ethanol was added as solvent and the reaction was carried out under hydrogen atmosphere. The reaction pressure was maintained at 2.5 MPa and the molar ratio of 2-bromoindanone to hydrogen was 1:50. The reaction was carried out at room temperature with stirring for 24 hours. Upon completion of the reaction, the palladium carbon catalyst was recovered by filtration and the solvent was removed by rotary evaporation. Finally 18.5 g of 2-bromo-2,3-dihydro-1H-indene (Compound II) was obtained as an oil in 90% yield.
References
[1] Patent: CN104945265, 2017, B. Location in patent: Paragraph 0036; 0037; 0038
2-BROMOINDAN Preparation Products And Raw materials
Raw materials
Preparation Products
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