H-HIS-AMC
- Product Name
- H-HIS-AMC
- CAS No.
- 191723-64-5
- Chemical Name
- H-HIS-AMC
- Synonyms
- 1600;H-HIS-AMC;H-L-His-AMC;L-His-AMC·TFA;H-His-AMC.TFA;H-HIS-AMC USP/EP/BP;H-His-AMC Trifluoroacetate salt;L-HISTIDINE 7-AMIDO-4-METHYLCOUMARIN;L-histidine 7-amindo-4-methylcoumarin;L-Histidine 7-amido-4-Methylcoumarine
- CBNumber
- CB4420116
- Molecular Formula
- C16H16N4O3
- Formula Weight
- 312.32
- MOL File
- 191723-64-5.mol
H-HIS-AMC Property
- Boiling point:
- 696.0±55.0 °C(Predicted)
- Density
- 1.413±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 12.69±0.20(Predicted)
N-Bromosuccinimide Price
- Product number
- H456035
- Product name
- L-Histidine7-amido-4-methylcoumarin
- Packaging
- 10mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 06078
- Product name
- L-Histidine 7-amido-4-methylcoumarin trifluoroacetate salt
- Purity
- ≥ 98% (Assay)
- Packaging
- 25MG
- Price
- $145
- Updated
- 2021/12/16
- Product number
- 7317AH
- Product name
- L-Histidine7-amido-4-methylcoumarin
- Packaging
- 25mg
- Price
- $246
- Updated
- 2021/12/16
- Product number
- 06078
- Product name
- L-Histidine7-amido-4-methylcoumarintrifluoroacetatesalt,98%(Assay)
- Purity
- 98%(Assay)
- Packaging
- 100MG
- Price
- $324.8
- Updated
- 2021/12/16
- Product number
- AAA0005608
- Product name
- L-HISTIDINE-7-AMIDO-4-METHYLCOUMARIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.41
- Updated
- 2021/12/16
H-HIS-AMC Chemical Properties,Usage,Production
Chemical Properties
Off-white to white powder
Uses
L-Histidine 7-amido-4-methylcoumarin is an enzyme substrate. Substrates of glycosidases, phosphatases and esterases are commonly employed in microbiology, food/water, environmental and ELISA testing. Assays of peptidases are more important in clinical enzyme assays and AMC is the fluorophore employed in most of these substrates. AMC is extremely versatile since the carboxy-terminus of any amino acid or peptide can be linked to it. Most enzymes are tolerant towards the AMC structure. Typically, kinetics of enzyme reactions remain undisturbed and few inhibitory effects are observed. Due to the low basicity of the amino group, AMC is not subject to acid base equilibrium at physiological pH. Therefore, assays using AMC substrates are rather tolerant of pH.