ChemicalBook > CAS DataBase List > Porcupine-IN-1

Porcupine-IN-1

Product Name
Porcupine-IN-1
CAS No.
2036044-77-4
Chemical Name
Porcupine-IN-1
Synonyms
CS-2802;PORCN-IN-1;Porcupine-IN-1;Porcn inhibitor 1;Porcupine-IN-1 free base;Porcupine,inhibit,PorcnIN1,Inhibitor,Porcn IN 1;9H-Carbazole-2-carboxamide, N-[(3-fluoro-2'-methyl[2,4'-bipyridin]-5-yl)methyl]-
CBNumber
CB44204130
Molecular Formula
C25H19FN4O
Formula Weight
410.44
MOL File
2036044-77-4.mol
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Porcupine-IN-1 Property

storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: slightly soluble
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25834
Product name
Porcupine-IN-1
Purity
≥98%
Packaging
1mg
Price
$75
Updated
2024/03/01
Cayman Chemical
Product number
25834
Product name
Porcupine-IN-1
Purity
≥98%
Packaging
5mg
Price
$281
Updated
2024/03/01
Cayman Chemical
Product number
25834
Product name
Porcupine-IN-1
Purity
≥98%
Packaging
10mg
Price
$488
Updated
2024/03/01
Cayman Chemical
Product number
25834
Product name
Porcupine-IN-1
Purity
≥98%
Packaging
25mg
Price
$938
Updated
2024/03/01
ChemScene
Product number
CS-0041562
Product name
Porcn-IN-1
Purity
99.08%
Packaging
10mg
Price
$250
Updated
2021/12/16
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Porcupine-IN-1 Chemical Properties,Usage,Production

Description

Porcupine-IN-1 is an inhibitor of the Wnt and hedgehog signaling pathways (IC50s = 0.5 and 71 nM, respectively, in cell-based reporter assays). It inhibits secretion of Wnt3A from Wnt3A-transfected HEK293T cells when used at a concentration of 0.1 μM, indicating inhibition of porcupine, an enzyme that catalyzes palmitoylation of Wnt proteins.

Uses

Porcupine-IN-1, is a potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.

Porcupine-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Porcupine-IN-1 Suppliers

China 33 India 1 United States 6 Global 40
Sichuan Wei Keqi Biological Technology Co., Ltd.
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2036044-77-4, Porcupine-IN-1Related Search:


  • Porcupine-IN-1
  • PORCN-IN-1
  • Porcn inhibitor 1
  • CS-2802
  • 9H-Carbazole-2-carboxamide, N-[(3-fluoro-2'-methyl[2,4'-bipyridin]-5-yl)methyl]-
  • Porcupine-IN-1 free base
  • Porcupine,inhibit,PorcnIN1,Inhibitor,Porcn IN 1
  • 2036044-77-4