Porcupine-IN-1
- Product Name
- Porcupine-IN-1
- CAS No.
- 2036044-77-4
- Chemical Name
- Porcupine-IN-1
- Synonyms
- CS-2802;PORCN-IN-1;Porcupine-IN-1;Porcn inhibitor 1;Porcupine-IN-1 free base;Porcupine,inhibit,PorcnIN1,Inhibitor,Porcn IN 1;N-((3-Fluoro-2'-methyl-[2,4'-bipyridin]-5-yl)methyl)-9H-carbazole-2-carboxamide;9H-Carbazole-2-carboxamide, N-[(3-fluoro-2'-methyl[2,4'-bipyridin]-5-yl)methyl]-
- CBNumber
- CB44204130
- Molecular Formula
- C25H19FN4O
- Formula Weight
- 410.44
- MOL File
- 2036044-77-4.mol
Porcupine-IN-1 Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: slightly soluble
- form
- A crystalline solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 25834
- Product name
- Porcupine-IN-1
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $75
- Updated
- 2024/03/01
- Product number
- 25834
- Product name
- Porcupine-IN-1
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $281
- Updated
- 2024/03/01
- Product number
- 25834
- Product name
- Porcupine-IN-1
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $488
- Updated
- 2024/03/01
- Product number
- 25834
- Product name
- Porcupine-IN-1
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $938
- Updated
- 2024/03/01
- Product number
- CS-0041562
- Product name
- Porcn-IN-1
- Purity
- 99.08%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
Porcupine-IN-1 Chemical Properties,Usage,Production
Description
Porcupine-IN-1 is an inhibitor of the Wnt and hedgehog signaling pathways (IC50s = 0.5 and 71 nM, respectively, in cell-based reporter assays). It inhibits secretion of Wnt3A from Wnt3A-transfected HEK293T cells when used at a concentration of 0.1 μM, indicating inhibition of porcupine, an enzyme that catalyzes palmitoylation of Wnt proteins.
Uses
Porcupine-IN-1, is a potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.
Porcupine-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Porcupine-IN-1 Suppliers
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