ChemicalBook > CAS DataBase List > 5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER
5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER
- Product Name
- 5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 223519-11-7
- Chemical Name
- 5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- 3-Amino-5-bromo-4-methyl-benzoi;methyl 3-amino-5-bromo-4-methylbenzoate;3-AMINO-5-BROMO-4-METHYL-BENZOIC ACID METHYL ESTER;5-AMINO-3-BROMO-4-METHYL-1-BENZOIC ACID METHYL ESTER;Benzoic acid, 3-amino-5-bromo-4-methyl-, methyl ester;5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER
- CBNumber
- CB4425146
- Molecular Formula
- C9H10BrNO2
- Formula Weight
- 244.09
- MOL File
- 223519-11-7.mol
More
Less
5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER Property
- Boiling point:
- 344.7±37.0 °C(Predicted)
- Density
- 1.506±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 2.23±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
More
Less
N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0061185
- Product name
- Methyl3-amino-5-bromo-4-methylbenzoate
- Packaging
- 100mg
- Price
- $103
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0061185
- Product name
- Methyl3-amino-5-bromo-4-methylbenzoate
- Packaging
- 1g
- Price
- $341
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0061185
- Product name
- Methyl3-amino-5-bromo-4-methylbenzoate
- Packaging
- 5g
- Price
- $1022
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0061185
- Product name
- Methyl3-amino-5-bromo-4-methylbenzoate
- Packaging
- 250mg
- Price
- $171
- Updated
- 2021/12/16
Chemenu
- Product number
- CM124485
- Product name
- methyl3-amino-5-bromo-4-methylbenzoate
- Purity
- 95%
- Packaging
- 1g
- Price
- $234
- Updated
- 2021/12/16
More
Less
5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
223519-08-2
223519-11-7
General procedure for the synthesis of methyl 3-amino-5-bromo-4-methyl-4-methylbenzoate from methyl 3-bromo-4-methyl-5-nitrobenzoate: Methyl 3-bromo-4-methyl-5-nitrobenzoate (8.50 g, 31.0 mmol), acetic acid (20 mL), and tetrahydrofuran (170 mL) were added to a 500 mL single-necked flask, followed by batchwise addition of iron powder (8.68 g, 155 mmol). The reaction mixture was stirred at 75 °C for 12 hours. Upon completion of the reaction, the mixture was cooled to room temperature, filtered to remove insoluble solids and the filtrate was concentrated under vacuum. Water (500 mL) was added to the concentrated residue and extracted with ethyl acetate (100 mL × 2). The organic phases were combined, washed with saturated brine (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under vacuum. The residue was purified by silica gel column chromatography with the eluent of ethyl acetate/petroleum ether (v/v = 1/10) to afford methyl 3-amino-5-bromo-4-methylbenzoate as a light yellow solid (5.52 g, 73% yield). Mass spectrum (ESI-API, positive ion mode) m/z: 244.9 [M + 2]+.
References
[1] Tetrahedron, 2014, vol. 70, # 2, p. 318 - 326
[2] Patent: WO2017/36404, 2017, A1. Location in patent: Page/Page column 69; 70; 80; 81
5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER Suppliers
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 0512-69369885
- Fax
- 0512-69369880
- sales@anichem.com.cn
- Country
- China
- ProdList
- 495
- Advantage
- 55
- Tel
- 18151128828
- Fax
- -
- hc-sales@foxmail.com
- Country
- China
- ProdList
- 2647
- Advantage
- 55
- Tel
- 0513-0513-51005092 13390947892
- Fax
- 0513-51005092
- tashiyxy@163.com
- Country
- China
- ProdList
- 838
- Advantage
- 58
- Tel
- 15332490153
- Fax
- QQ 2725398181
- newprochem@126.com
- Country
- China
- ProdList
- 991
- Advantage
- 55
- Tel
- 17317567081
- info@coreuni.com
- Country
- China
- ProdList
- 201
- Advantage
- 55
- Tel
- 025-66162170
- Fax
- 025-66162170
- Country
- China
- ProdList
- 7181
- Advantage
- 55
- Tel
- 18066080842 13952020641
- Fax
- 025-58912720
- bamd@foxmail.com
- Country
- China
- ProdList
- 759
- Advantage
- 55
- Tel
- 18995639250
- Fax
- -
- huangxq@graphe-tech.com
- Country
- China
- ProdList
- 500
- Advantage
- 55
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 025-52791040 18652036685
- haozhongwen@126.com
- Country
- China
- ProdList
- 767
- Advantage
- 58
- Tel
- 025-58867862 18751812725
- Fax
- 02558867862
- sales@ace-pharm.com
- Country
- China
- ProdList
- 1985
- Advantage
- 58
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
- Country
- China
- ProdList
- 19987
- Advantage
- 58
- Tel
- +86-0571-88938639 +8617705817739
- Fax
- +86-571-88938652，+86-571- 88492614
- info@dycnchem.com
- Country
- China
- ProdList
- 52846
- Advantage
- 58
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- chemwill_asia@126.com
- Country
- CHINA
- ProdList
- 23912
- Advantage
- 58
- Tel
- +86-023-6139-8061 +86-86-13650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39927
- Advantage
- 58
- Tel
- 15151934985
- sales@yingsapharm.com
- Country
- China
- ProdList
- 5173
- Advantage
- 58
- Tel
- 0519-68985668 13685222090
- Fax
- qq735434464
- sales@kechem.cn
- Country
- China
- ProdList
- 26028
- Advantage
- 58
- Tel
- 0371-0371-53736046 13393710386
- Fax
- QQ:2853979814
- 2853979814@qq.com
- Country
- China
- ProdList
- 9948
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 15092083467
- 18660263263@163.com
- Country
- China
- ProdList
- 2811
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44119
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 40000
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39653
- Advantage
- 58
- Tel
- 15995034354
- purchase@chochem.cn
- Country
- China
- ProdList
- 2704
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50464
- Advantage
- 58
- Tel
- 13611612777
- 3627377363@qq.com
- Country
- China
- ProdList
- 4015
- Advantage
- 58
- Tel
- 021-57520305 13795461237
- zhuruyan@jskchem.com
- Country
- China
- ProdList
- 49234
- Advantage
- 58
- Tel
- 021-50795510 4000665055
- SY06@accelachem.com
- Country
- China
- ProdList
- 7551
- Advantage
- 58
- Tel
- 16621224781
- syy@titansci.com
- Country
- China
- ProdList
- 2896
- Advantage
- 58
- Tel
- 19355912709
- 690231469@qq.com
- Country
- China
- ProdList
- 7593
- Advantage
- 58
- Tel
- 17717618050
- zllg@gh-reagent.com
- Country
- China
- ProdList
- 10420
- Advantage
- 58
- Tel
- 02152215958
- 47697177@qq.com
- Country
- China
- ProdList
- 10011
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- sales@coreychem.com
- Country
- China
- ProdList
- 29846
- Advantage
- 58
- Tel
- +8615936229464
- candice@collab-med.com
- Country
- China
- ProdList
- 986
- Advantage
- 58
- Tel
- +8613817748580
- Fax
- 021-50175322
- cooperation@kean-chem.com
- Country
- China
- ProdList
- 40066
- Advantage
- 58
- Tel
- +8615303909093
- sales@compound-net.com
- Country
- China
- ProdList
- 2914
- Advantage
- 58
- Tel
- +86-2759207851; +8618007136271
- hk@fortunachem.com
- Country
- China
- ProdList
- 5990
- Advantage
- 58
- Tel
- +86-371-86557731 +86-13613820652
- Fax
- 86-0371-86557731
- info@fdachem.com
- Country
- China
- ProdList
- 20135
- Advantage
- 58
- Tel
- +86-029-86185165 +8618629664246
- guoyuan@eastchinapharm.com
- Country
- China
- ProdList
- 1615
- Advantage
- 58
- Tel
- +8618058761490
- info@gihichemicals.com
- Country
- China
- ProdList
- 49934
- Advantage
- 58
- Tel
- +86-85511178;
- peter68@ptchemgroup.com
- Country
- China
- ProdList
- 35425
- Advantage
- 58
- Tel
- +86-0571-85585865 +8613336024896
- CB@aromsyn.com
- Country
- China
- ProdList
- 19183
- Advantage
- 58
More
Less
View Lastest Price from 5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER manufacturers
Career Henan Chemical Co
- Product
- 5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER 223519-11-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-08-15
223519-11-7, 5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTERRelated Search:
3-Bromo-4-methylbenzoic acid
3-AMINO-5-BROMOBENZOATE
5-AMINO-3-BROMO-4-METHYL-1-CARBOXYLIC ACID METHYL ESTER
Methyl 3-bromo-4-methylbenzoate
3-BROMO-4-METHYL-5-NITROBENZOIC ACID METHYL ESTER