ChemicalBook > CAS DataBase List > 3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID

3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID

Product Name
3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
CAS No.
53985-49-2
Chemical Name
3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
Synonyms
3-Chloro-5-carboxybenzotrifluoride;3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID;Benzoic acid, 3-chloro-5-(trifluoromethyl)-;3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid
CBNumber
CB4435008
Molecular Formula
C8H4ClF3O2
Formula Weight
224.56
MOL File
53985-49-2.mol
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3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Property

Melting point:
98-101℃
Boiling point:
263℃
Density 
1.523
Flash point:
113℃
storage temp. 
Sealed in dry,Room Temperature
Appearance
White to off-white Solid
Water Solubility 
Soluble in water.
InChI
InChI=1S/C8H4ClF3O2/c9-6-2-4(7(13)14)1-5(3-6)8(10,11)12/h1-3H,(H,13,14)
InChIKey
IDLOGBMWOUINGG-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(C(F)(F)F)=CC(Cl)=C1
CAS DataBase Reference
53985-49-2
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
C381525
Product name
3-Chloro-5-(trifluoromethyl)benzoicAcid
Packaging
100mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
PC6011
Product name
3-Chloro-5-(trifluoromethyl)benzoicacid
Packaging
1g
Price
$14
Updated
2021/12/16
Oakwood
Product number
038345
Product name
3-Chloro-5-(trifluoromethyl)benzoicacid
Purity
99%
Packaging
1g
Price
$19
Updated
2021/12/16
Matrix Scientific
Product number
009469
Product name
3-Chloro-5-(trifluoromethyl)benzoic acid
Purity
95%
Packaging
1g
Price
$19
Updated
2021/12/16
Apolloscientific
Product number
PC6011
Product name
3-Chloro-5-(trifluoromethyl)benzoicacid
Packaging
5g
Price
$41
Updated
2021/12/16
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3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties,Usage,Production

Uses

2-Chloro-5-(trifluoromethyl)benzoic acid may be used as surrogate standard to investigate the exposure and home contamination in urine and hand wipe samples collected from farmers.

Synthesis


A solution of tBuONO (35.2 g) and CuCl (38.6 g) in CH3CN (375 mL) was warmed to 45-50° C. The compound (50.0 g) obtained in step 2 was added slowly while cooling the reaction mixture to maintain 45-50° C. After stirring at 50° C. for 30 min, the mixture was cooled to 10° C. 6N Hydrochloric acid (250 mL) was added and the mixture was stirred for 10 min. The resultant product was extracted twice with ethyl acetate. The organic layer was-washed with 10% aqueous citric acid solution and water and dried, and the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (solvent gradient; 10→25% ethyl acetate/hexane) to give 3-chloro-5-(trifluoromethyl)benzoic acid (33.1 g, 60%) as a white powder.

3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Suppliers

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View Lastest Price from 3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID 53985-49-2
Price
US $101.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-28
Career Henan Chemical Co
Product
3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID 53985-49-2
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
500kg/month
Release date
2019-08-01

53985-49-2, 3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACIDRelated Search:

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  • 3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID
  • 3-Chloro-5-carboxybenzotrifluoride
  • 3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid
  • Benzoic acid, 3-chloro-5-(trifluoromethyl)-
  • 53985-49-2