TRIMETHYLTIN HYDROXIDE

Product Name: TRIMETHYLTIN HYDROXIDE
CAS No.: 56-24-6
Chemical Name: TRIMETHYLTIN HYDROXIDE
Synonyms: trimethylstannanol;trimethylstannylhydroxide;TRIMETHYLTIN(IV) HYDROXIDE;hydroxytrimethylstannane;Me3SnOH;trimethylhydroxytin;hydroxytrimethyltin;hydroxytrimethyl-ti;rimethyltin,hydrate;trimethyl-tihydroxide
CBNumber: CB4440435
Molecular Formula: C3H10OSn
Formula Weight: 180.82
MOL File: 56-24-6.mol

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TRIMETHYLTIN HYDROXIDE Property

Melting point:: 118°C
Boiling point:: 80°C
RTECS: WH8400000
Flash point:: 26℃
solubility: Chloroform (Soluble, Sonicated), Methanol (Slightly, Sonicated), Water (Sparingly)
form: Powder
pka: 6.36±0.70(Predicted)
color: White
Water Solubility: Soluble in water.
Sensitive: Moisture Sensitive
Exposure limits: ACGIH: TWA 0.1 mg/m3; STEL 0.2 mg/m3 (Skin)
NIOSH: IDLH 25 mg/m3; TWA 0.1 mg/m3
InChI: InChI=1S/3CH3.H2O.Sn/h3*1H3;1H2;/q;;;;+1/p-1
InChIKey: OJZNYUDKNVNEMV-UHFFFAOYSA-M
SMILES: [Sn](O)(C)(C)C
EPA Substance Registry System: Stannane, hydroxytrimethyl- (56-24-6)

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Safety

Risk Statements: 20/21/22
Safety Statements: 22-36/37/39-45
RIDADR: 3146
HazardClass: 6.1
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P320Specific treatment is urgent (see … on this label).

P330Rinse mouth.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS025240
Product name: Trimethylstannanol
Purity: AldrichCPR
Packaging: 100MG
Price: $103
Updated: 2025/07/31

Strem Chemicals

Product number: 93-5085
Product name: Trimethyltin hydroxide, 98%
Packaging: 2g
Price: $94
Updated: 2024/03/01

Strem Chemicals

Product number: 93-5085
Product name: Trimethyltin hydroxide, 98%
Packaging: 10g
Price: $375
Updated: 2024/03/01

Strem Chemicals

Product number: 93-5085
Product name: Trimethyltin hydroxide, 98%
Packaging: 50g
Price: $1512
Updated: 2024/03/01

TRC

Product number: T797615
Product name: TrimethyltinHydroxide
Packaging: 500mg
Price: $115
Updated: 2021/12/16

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TRIMETHYLTIN HYDROXIDE Chemical Properties,Usage,Production

Chemical Properties

Trimethyltin hydroxide is a colorless, white crystals. It is soluble in water and many organic solvents. It is commercially available in the form of large, needle-shaped, crystals with a significant propensity for twinning along the needle axis. The twinning of the trimethyltin hydroxide needle shaped crystals makes finding a single crystal for data collection very difficult.

Uses

Trimethyltin hydroxide is used in the synthesis of modified thymines, which is useful as inhibitors of RNase A. It is also used in the preparation of ketoheterocycle inhibitors of fatty acid amide inhibitors. It reacts with 2,2-disubstituted benzothiazolines to form trialkyltin derivatives of sulphur containing Schiff base complexes.

Reactions

The synthesis of N-Boc-N-(2-(tritylthio)ethoxy)glycine (4) is illustrated in Scheme 2. O-(2-(tritylthio)ethyl)hydroxylamine (1) was synthesized using the literature method. The aminooxy group was then protected with Boc, followed by alkylation with methyl bromoacetate in the presence of sodium hydride. Saponification of the methyl ester with trimethyltin hydroxide afforded N-Boc-N-(2-(tritylthio)ethoxy)glycine (4) in an overall yield of 19% after three steps of reactions. The Boc and Trt protecting groups in building block 4 are stable to Fmoc SPPS and are readily removable by treatment with trifluoroacetic acid (TFA).

Hazard

A poison.

References

[1] Anderson, Kirsty M., et al. "Trimethyltin hydroxide: a crystallographic and high Z′ curiosity." Crystal Growth & Design, 2011, 11 3: 820-826. DOI:10.1021/cg101464j.
[2] K. C. NICOLAOU PROF. DR. A Mild and Selective Method for the Hydrolysis of Esters with Trimethyltin Hydroxide?[J]. Angewandte Chemie International Edition, 2005, 44 9: 1378-1382. DOI:10.1002/anie.200462207.
[3] ROBIN K HARRIS Patrick R Kenneth J Packer. High-resolution Tin-119 NMR of solid trimethyltin hydroxide[J]. Journal of Magnetic Resonance (1969), 1985, 61 3: Pages 564-566. DOI:10.1016/0022-2364(85)90199-4.
[4] LINGLING PENG, AIMIN SONG* N-tert-Butoxycarbonyl-N-(2-(tritylthio)ethoxy)glycine as a Building Block for Peptide Ubiquitination[J]. Bioconjugate Chemistry Bioconjugate, 2024, 35 2: 245-253. DOI:10.1021/acs.bioconjchem.3c00541.

TRIMETHYLTIN HYDROXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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TRIMETHYLTIN HYDROXIDE Suppliers

China 66 Germany 3 India 2 Japan 1 Russia 1 United Kingdom 3 United States 11 Global 87

Domole Scientific

Tel: 13275595566
Fax: -
Email: domole@infsci.com
Country: China
ProdList: 299
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
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Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
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Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
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Conier Chem & Pharma Co.,Ltd,

Tel: 023-62879767 13996269627;
Fax: +86-28-84559521
Email: sales@conier.com
Country: China
ProdList: 283
Advantage: 56

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
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View Lastest Price from TRIMETHYLTIN HYDROXIDE manufacturers

Shaanxi Didu New Materials Co. Ltd

Product: Hydroxytrimethylstannane 56-24-6
Price: US $13.00/g
Min. Order: 1g
Purity: 99.0% Min
Supply Ability: 1kg
Release date: 2025-04-03

56-24-6, TRIMETHYLTIN HYDROXIDERelated Search:

Bis(tributyltin) oxide Triphenyltin acetate Fentin hydroxide TRI-N-BUTYLTIN ACETATE BIS(TRIPHENYLTIN) OXIDE TRI-N-BUTYLTIN METHOXIDE Trimethyltin hydroxide BIS(TRIMETHYLSILYL)TRIBUTYLTINPHOSPHATE TRIBUTYLTIN ETHOXIDE TRIBUTYLTIN SEBACATE tin hydroxide TRIBUTYLTIN SALICYLATE BIS(TRIPROPYL TIN)OXIDE TRIPHENYL TIN-P-ACETAMINO BENZOATE TRIBUTYL(8-QUINOLYLOXY)TIN BIS(TRI-N-BUTYLTIN) ITACONATE TRI-N-BUTYLTIN 2,4-DICHLOROPHENOLATE TRI-N-BUTYLTIN PROPIONATE

trimethylstannylhydroxide

hydroxytrimethyltin

trimethylhydroxytin

trimethylstannanol

trimethyl-tihydroxide

TIN TRIMETHYL HYDROXIDE

Trimethyltinhydroxide,98%

STANNANE,HYDROXYTRIMETHYL-

Hydroxytrimethyltin(IV)

Trimethylstannyl alcohol

Trimethyltin hydroxide, 98% (CH3)3SnOH F.W.180.80

TriMethyltin hydroxide, 98% (CH3)3SnOH

TRIMETHYLTIN HYDROXIDE

TRIMETHYLTIN(IV) HYDROXIDE

hydroxytrimethyl-stannan

hydroxytrimethylstannane

hydroxytrimethyl-ti

Stannane, hydroxytrimethyl- (8CI,9CI)

rimethyltin,hydrate

Me3SnOH

56-24-6

C3H10OSn

C3H10SnO

CH33SnOH

organotin compound