H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH

Product Name: H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH
CAS No.: 92915-79-2
Chemical Name: H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH
Synonyms: OVA (323-339);ISQAVHAAHAEINEAGR;OVA (323-339) TFA salt;H2N-ISQAVHAAHAEINEAGR-OH;OVALBUMIN CHICKEN (323-339);OVA (323-339), free acid, chicken;OVA (323-339) (CHICKEN, JAPANESE QUAIL);OVALBUMIN (323-339) (CHICKEN, JAPANESE QUAIL);ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG;H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH
CBNumber: CB4440910
Molecular Formula: C74H120N26O25
Formula Weight: 1773.9
MOL File: 92915-79-2.mol

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H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH Property

Density: 1.52±0.1 g/cm3(Predicted)
storage temp.: -15°C
pka: 3.33±0.10(Predicted)
form: lyophilized powder
color: white
Water Solubility: water, double-distilled: soluble
Sequence: Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O1641
Product name: Ovalbumin (323-339) (chicken, Japanese quail)
Packaging: 1MG
Price: $188.81
Updated: 2025/07/31

Sigma-Aldrich

Product number: O1641
Product name: Ovalbumin (323-339) (chicken, Japanese quail)
Packaging: 5MG
Price: $755.7
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: PEP0002725
Product name: H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH
Purity: 95.00%
Packaging: 5MG
Price: $786.45
Updated: 2021/12/16

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H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH Chemical Properties,Usage,Production

Uses

Ovalbumin (323-339) (chicken, Japanese quail) has been used to induce allergic asthma in mice.

General Description

Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4⁺ T cell epitopes.

Biochem/physiol Actions

With the help of two functionally distinct registers ovalbumin (323-339) peptide can bind to histocompatibility complex class II I-A(d) protein.

in vivo

OVA Peptide (323-339) represents a T and B cell epitope of OVA, which is important in the generation and development of immediate hypersensitivity responses in BALB/c mice. Daily aerosolization of OVA Peptide (323-339) for 20 minutes over a period of 10 days has been as effective in the stimulation of a serum anti-OVA IgE antibody response as sensitization to native OVA by the same route. After sensitization to native OVA, the majority of the IgE anti-OVA response is directed against OVA Peptide (323-339). Evaluated by hematoxylin/eosin and major basic protein immunohistochemical stainings, OVA and OVA Peptide (323-339) induce similar lung inflammation. Interestingly, significant serum total IgE and OVA-specific IgE are observed in OVA mice when compared to saline control. OVA Peptide (323-339) mice show higher serum OVA-specific IgE, OVA Peptide (323-339)-specific IgE, IL-4 and lower IFN-γ similar to OVA mice. The proliferative response to OVA is found in cultured splenocytes of both OVA and OVA Peptide (323-339) mice, while the similar proliferative response to OVA Peptide (323-339) is only observed in the splenocytes of OVA Peptide (323-339)-sensitized and challenged mice. Although OVA Peptide (323-339) induces a Th2-like response in the mouse model as does OVA, OVA Peptide (323-339) has clearly limited immunogenic potency to activate OVA-sensitized and challenged mice splenocytes, unlike OVA^[2].

H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH Suppliers

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92915-79-2, H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OHRelated Search:

L-Leucine, L-seryl-L-isoleucyl-L-isoleucylglycyl-L-phenylalanyl-L-α-glutamyl-L-lysyl- L-Leucine, L-lysyl-L-valyl-L-valyl-L-arginyl-L-phenylalanyl-L-α-aspartyl-L-lysyl- OVA Peptide (257-264) TFA OVA(241-270) FITC lable L-Alanine, L-alanyl-L-alanyl-L-histidyl-L-alanyl-L-α-glutamyl-L-isoleucyl-L-asparaginyl-L-α-glutamyl- (9CI) OVA sequence (323-336) OVA Peptide OVALBUMIN H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH

OVALBUMIN CHICKEN (323-339)

OVALBUMIN (323-339) (CHICKEN, JAPANESE QUAIL)

OVA (323-339)

OVA (323-339) (CHICKEN, JAPANESE QUAIL)

H2N-ISQAVHAAHAEINEAGR-OH

L-Arginine,L-isoleucyl-L-seryl-L-glutaminyl-L-alanyl-L-valyl-L-histidyl-L-alanyl-L-alanyl-L-histidyl-L-alanyl-L-a-glutamyl-L-isoleucyl-L-asparaginyl-L-a-glutamyl-L-alanylglycyl-

ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG

H-ILE-SER-GLN-ALA-VAL-HIS-ALA-ALA-HIS-ALA-GLU-ILE-ASN-GLU-ALA-GLY-ARG-OH

ISQAVHAAHAEINEAGR

OvalbuMin (323-339) (chicken, japanese quail) OVA (323-339) (chicken, japanese quail)

L-Arginine, L-isoleucyl-L-seryl-L-glutaminyl-L-alanyl-L-valyl-L-histidyl-L-alanyl-L-alanyl-L-histidyl-L-alanyl-L-α-glutamyl-L-isoleucyl-L-asparaginyl-L-α-glutamyl-L-alanylglycyl-

OVA (323-339), free acid, chicken

OVA (323-339) TFA salt

92915-79-2

C74H120N26O25

Peptide

Various Peptides