ChemicalBook > CAS DataBase List > FTI-276

FTI-276

Product Name
FTI-276
CAS No.
170006-72-1
Chemical Name
FTI-276
Synonyms
FTI-276;ZIXDDEATQSBHHL-BEFAXECRSA-N;FTI-276 trifluoroacetate salt;N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-;N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT
CBNumber
CB4442484
Molecular Formula
C21H27N3O3S2
Formula Weight
433.59
MOL File
Mol file
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FTI-276 Property

Boiling point:
715.6±60.0 °C(Predicted)
Density 
1.272±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: >5 mg/mL, soluble
pka
3.54±0.10(Predicted)
form 
solid
color 
off-white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
344550
Product name
FTI-276
Purity
A highly potent and selective CAAX peptidomimetic of the carboxyl terminal of Ras proteins that inhibits farnesyl transferase (FTase) in vitro (IC?? = 500 pM).
Packaging
250μG
Price
$245
Updated
2024/03/01
Usbiological
Product number
255340
Product name
FTI 276
Packaging
1mg
Price
$389
Updated
2021/12/16
ChemScene
Product number
CS-0009428
Product name
FTI276
Packaging
5mg
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0066839
Product name
FTI-276 TRIFLUOROACETATE SALT
Purity
95.00%
Packaging
1MG
Price
$676.71
Updated
2021/12/16
ChemScene
Product number
CS-0009428
Product name
FTI276
Packaging
10mg
Price
$680
Updated
2021/12/16
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FTI-276 Chemical Properties,Usage,Production

Uses

N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine Trifluoroacetate Salt is a useful intermediate.

Definition

ChEBI: (2S)-2-[[[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-phenylphenyl]-oxomethyl]amino]-4-(methylthio)butanoic acid is a methionine derivative.

Biochem/physiol Actions

FTI-276 is a highly potent RasCAAX peptidomimetic. FTI-276 antagonizes both H and K-Ras oncogenic signaling. It is an inhibitor of farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM and is an anti-cancer agent.

FTI-276 Preparation Products And Raw materials

Raw materials

Preparation Products

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FTI-276 Suppliers

China 30 Japan 2 Switzerland 1 United Kingdom 2 United States 9 Global 44
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
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3bsc@sina.com
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China
ProdList
15839
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69
Sigma-Aldrich
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021-61415566 800-8193336
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orderCN@merckgroup.com
Country
China
ProdList
51456
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80
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52849
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
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China
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24648
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58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
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9272
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58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
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China
ProdList
49979
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58
Shanghai Yijie Biological Technology Co., Ltd.
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--
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SHYIJIEBIO@126.COM
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CHINA
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3510
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Shanghai Qiming Biological Technology Co., Ltd.
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--
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Beijing Bai Ao Si Biotechnology Co., Ltd.
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--
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yangmei@bioneeds.net
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CHINA
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Beijing Taize Jiaye Technology Development Co., Ltd.
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--
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Fujifilm Wako (Guangzhou) Trading Co., Ltd.
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Guangzhou Weijia Technology Co., Ltd.
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Shanghai Ziqi Biological Technology Co., Ltd.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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--
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Shanghai Haoran Biotechnology Co., Ltd.
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--
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Dongguan Biaobiao Experimental Equipment Technology Co., Ltd.
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--
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Shanghai Hao Biological Technology Co., Ltd.
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Beijing Shengke Boyuan Biotechnology Co., Ltd.
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Beijing Fubo Biotechnology Co., Ltd.
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Beijing Taize Ruida Technology Co., Ltd.
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Wuhan Boot Biotechnology Co., Ltd.
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Beijing Zhijie Fangyuan Technology Co., Ltd.
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Beijing baierdi biotechnology co. LTD
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Xiamen Research Biotechnology Co., Ltd.
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Xiamen Huijia Biological Technology Co., Ltd.
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Beijing Bi Orange Blue Biotechnology Co., Ltd.
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Beijing Xiangsheng Xingye Technology Co., Ltd.
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5130
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170006-72-1, FTI-276Related Search:


  • N-[4-[2-(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE TRIFLUOROACETATE SALT
  • N-[2-PHENYL-4-N[2(R)-AMINO-3-MERCAPTOPROPYLAMINO BENZOYL]-METHIONINE, TFA
  • FTI-276
  • FTI-276 trifluoroacetate salt
  • ZIXDDEATQSBHHL-BEFAXECRSA-N
  • L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-
  • 170006-72-1
  • C21H27N3O3S2C2HF3O2
  • C23H28F3N3O5S2