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D-(+)-Maltose monohydrate

Product Name
D-(+)-Maltose monohydrate
CAS No.
6363-53-7
Chemical Name
D-(+)-Maltose monohydrate
Synonyms
D-MALTOSE;MALTOSE MONOHYDRATE;D-MALTOSE MONOHYDRATE;Maltose H;MALT SUGAR;MALTOBIOSE;D-MALATOSE;Maltose RS;MALTOSE H2O;Maltose,92%
CBNumber
CB4442570
Molecular Formula
C12H24O12
Formula Weight
360.31
MOL File
6363-53-7.mol
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D-(+)-Maltose monohydrate Property

Melting point:
119-121 °C (dec.)(lit.)
alpha 
137 º (c=4, H2O, NH3)
storage temp. 
room temp
solubility 
H2O: 50 mg/mL
form 
powder
color 
White
PH
5.0-7.0 (25℃, 0.5M in H2O)
optical activity
[α]20/D +130±2°, 24 hr, c = 4% in H2O
Water Solubility 
1080 g/L (20 ºc)
λmax
λ: 260 nm Amax: 0.08
λ: 280 nm Amax: 0.07
Merck 
14,5714
BRN 
5784659
CAS DataBase Reference
6363-53-7(CAS DataBase Reference)
NIST Chemistry Reference
«beta»-Maltose monohydrate(6363-53-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
33-63-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
RTECS 
OO5250000
F 
3
TSCA 
Yes
HS Code 
17029010
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
63418
Product name
D-(+)-Maltose monohydrate
Purity
BioUltra, ≥99.0% (HPLC)
Packaging
25g
Price
$79
Updated
2024/03/01
Sigma-Aldrich
Product number
47288
Product name
D-(+)-Maltose monohydrate
Purity
analytical standard
Packaging
500mg
Price
$37
Updated
2024/03/01
Sigma-Aldrich
Product number
1375025
Product name
Maltose monohydrate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
500mg
Price
$519
Updated
2024/03/01
Sigma-Aldrich
Product number
1.05910
Product name
Maltose monohydrate
Purity
for microbiology
Packaging
500g
Price
$104
Updated
2024/03/01
Sigma-Aldrich
Product number
MX0160
Product name
Maltose, Monohydrate, Powder - CAS 6363-53-7 - Calbiochem
Packaging
10Kg
Price
$1790
Updated
2022/05/15
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D-(+)-Maltose monohydrate Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Chemical Properties

Maltose occurs as white crystals or as a crystalline powder. It is odorless and has a sweet taste approximately 30% that of sucrose.

Uses

A disaccharide commonly found in foods and commonly utilized in brewing processes.

Uses

D-(+)-Maltose monohydrate, is commonly found in foods and commonly utilized in brewing processes. It is also used in various culture media in the cell and tissue culture applications. D-(+)-Maltose Monohydrate is used as a substrate for α-glucosidase. It is also used as a substrate for the identification, differentiation and characterization of enzymes such as maltase(s); maltose α-D-glucosyltransferase(s); maltose-transporting ATPase(s); maltose O-acetyltransferase(s) and maltose epimerase(s) and phosphorylase(s). D-Maltose is used to study maltose-binding proteins and disaccharide transport systems.

Uses

D-Maltose, an α(1→4) linked disaccharide of D-glucose, is used as a substrate for the identification, differentiation and characterization of enzymes such as maltase(s); maltose α-D-glucosyltransferase(s); maltose-transporting ATPase(s); maltose O-acetyltransferase(s) and maltose epimerase(s) and phosphorylase(s). D-Maltose is used to study maltose-binding proteins and disaccharide transport systems.

Production Methods

Maltose monohydrate is prepared by the enzymatic degradation of starch.

General Description

Maltose monohydrate is commonly used as a tablet filler or excipient in pharmaceutical industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pharmaceutical Applications

Maltose is a disaccharide carbohydrate widely used in foods and pharmaceuticals. In parenteral products, maltose may be used as a source of sugar, particularly for diabetic patients.
Crystalline maltose is used as a direct-compression tablet excipient in chewable and nonchewable tablets.

Biochem/physiol Actions

Maltose is a disaccharide containing two glucose molecules with an α(1→4) glycosidic linkage. Maltose can be derived from starch in food through the action of amylase. Maltose can be found in many food products, including beer, cereals, and pasta.

Safety

Maltose is used in oral and parenteral pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material. However, there has been a single report of a liver transplantation patient with renal failure who developed hyponatremia following intravenous infusion of normal immunoglobulin in 10% maltose. The effect, which recurred on each of four successive infusions, resembled that of hyperglycemia and was thought to be due to accumulation of maltose and other osmotically active metabolites in the extracellular fluid.
LD50 (mouse, IV): 26.8 g/kg
LD50 (mouse, SC): 38.6 g/kg
LD50 (rabbit, IV): 25.2 g/kg
LD50 (rat, IP): 30.6 g/kg
LD50 (rat, IV): 15.3 g/kg
LD50 (rat, oral): 34.8 g/kg

storage

Maltose should be stored in a well-closed container in a cool, dry place.

Purification Methods

Purify maltose by chromatography from aqueous solution on to a charcoal/Celite (1:1) column, wash it with water to remove glucose and other monosaccharides, then elute it with aqueous 75% EtOH. Crystallise it from water, aqueous EtOH or EtOH containing 1% nitric acid. Dry it as the monohydrate at room temperature under vacuum over H2SO4 or P2O5. Also purify it by dissolving it in MeOH, evaporating to a syrup which on standing for 12hours in contact with 1/10th its volume of H2O gives crystals of the monohydrate. Its iodine number is 55.5. The osazone has m 200o(dec) and [] D 20 +58o (c 1.4, H2O). [Howarth et al. J Chem Soc 793 1937, Beilstein 17 III/IV 3057, 17 V 189.]

Incompatibilities

Maltose may react with oxidizing agents. A Maillard-type reaction may occur between maltose and compounds with a primary amine group, e.g. glycine, to form brown-colored products.

Regulatory Status

In the USA, maltose is considered as a food by the FDA and is therefore not subject to food additive and GRAS regulations. Included in the FDA Inactive Ingredients Database (oral solutions). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in parenteral products available in a number of countries worldwide.

D-(+)-Maltose monohydrate Preparation Products And Raw materials

Raw materials

LIQUID GLUCOSE β-Amylase Dextrin Maltose Fructose syrup

Preparation Products

IMP Gongzhulingmeisu POLYOXIN B Monosodium glutamate CARAMEL L-(+)Sodium glutamate Pullulan 3-Methyl-1-butanol POLYOXIN A
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D-(+)-Maltose monohydrate Suppliers

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View Lastest Price from D-(+)-Maltose monohydrate manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
D-(+)-Maltose monohydrate 6363-53-7
Price
US $99.00-66.00/kg
Min. Order
0.001kg
Purity
99%
Supply Ability
5000
Release date
2024-08-09
WUHAN FORTUNA CHEMICAL CO., LTD
Product
D-(+)-Maltose monohydrate 6363-53-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-09
Apeloa production Co.,Limited
Product
Maltose monohydrate 6363-53-7
Price
US $1.00/g
Min. Order
1g
Purity
0.98
Supply Ability
1000
Release date
2024-06-03

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