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NISTOSE

Product Name
NISTOSE
CAS No.
13133-07-8
Chemical Name
NISTOSE
Synonyms
NYSTOSE;fungitetraose;1,1-Kestotetraose;NISTOSE;1)-α-D-Glup;Nystose ,98%;β-D-Fruf-(2->1)-β-D-Fruf-(2<NISTOSE USP/EP/BP;1)-β-D-Fruf-(2->
CBNumber
CB4442631
Molecular Formula
C24H42O21
Formula Weight
666.58
MOL File
13133-07-8.mol
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NISTOSE Property

Melting point:
130-133℃
Boiling point:
1075.7±65.0 °C(Predicted)
Density 
1.84±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
10 ° (C=4, H2O)
storage temp. 
Sealed in dry,2-8°C
solubility 
H2O : 300 mg/mL (450.06 mM; Need ultrasonic and warming)
form 
Solid
pka
12.76±0.70(Predicted)
color 
White to off-white
BRN 
6171779
InChIKey
FLDFNEBHEXLZRX-DLQNOBSRSA-N
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29400090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
56218
Product name
Nystose
Purity
analytical standard
Packaging
100mg
Price
$175
Updated
2025/07/31
TCI Chemical
Product number
N0571
Product name
Nistose Trihydrate
Purity
>99.0%(HPLC)
Packaging
1g
Price
$318
Updated
2025/07/31
TRC
Product number
F862808
Product name
Fungitetraose
Packaging
50mg
Price
$375
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594659
Product name
Nystose
Packaging
100mg
Price
$408
Updated
2021/12/16
Chem-Impex
Product number
32399
Product name
Nistosetrihydrate,99%(HPLC)
Purity
99%(HPLC)
Packaging
1G
Price
$442.4
Updated
2021/12/16
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NISTOSE Chemical Properties,Usage,Production

Chemical Properties

White crystal

Uses

Fungitetraose is a part of the sugar mixture of Neosugar, sweetner.

Definition

ChEBI: Nystose is an oligosaccharide.

Synthesis

25101-99-9

13133-07-8

The general procedure for the synthesis of the target compound from the compound (CAS: 25101-99-9) was as follows: 100 mg of Hex4perAc was dissolved in 5 mL of methanol (MeOH), followed by the addition of 18 mg (0.3 eq.) of sodium methanolate (CH3ONa). After stirring the reaction mixture for 2.5 h at room temperature, Dowex 50Wx2 [H+] resin was added to neutralize the reaction solution. The resin was removed by filtration and the solvent was removed by distillation under reduced pressure. The residue was dissolved in water (H2O) and desalted using a Bio-Gel P-2 gel (10 mL). Finally, a white solid product (57 mg) was obtained by freeze-drying.

in vivo

Nystose (100 mg/kg, po for 14 days) enhances the intestinal IgA secretion and modulates systemic immune responses in BALB/c mouse models[2].
Nystose (40-160 mg/kg, po for 8 weeks) improves the bone density and bone microstructure in mouse models[3].

Animal Model:BALB/c mouse models[2]
Dosage:100 mg/kg
Administration:po for 14 days
Result:Inhibited the secretion of IL-2, IFN-γ, IL-12 and IL-4 by splenocytes.
Animal Model:ICR mouse models[3]
Dosage:40-160 mg/kg
Administration:po for 8 weeks
Result:Improved the bone density and bone microstructure.

target

IFN-γ | IL Receptor

References

[1] Patent: CN103638162, 2016, B. Location in patent: Paragraph 0056
[2] Molecules, 2018, vol. 23, # 2,

NISTOSE Preparation Products And Raw materials

Raw materials

Preparation Products

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NISTOSE Suppliers

China 191 France 1 Germany 2 India 4 Switzerland 1 United Kingdom 3 United States 11 Global 213
LIBIOS
Tel
--
Fax
--
Email
info@libios.fr
Country
France
ProdList
288
Advantage
58
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View Lastest Price from NISTOSE manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Nystose 13133-07-8
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-02-25
Career Henan Chemical Co
Product
NISTOSE 13133-07-8
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

13133-07-8, NISTOSERelated Search:

glaucocalyxin A Weeping Forsythia Extract CP2000 Verbascoside ISOMALTOTRIOSE 1-KESTOSE 1F-fructofuranosylnystose Fructo-oligosaccharide DP11/GF10 1,1,1,1-Kestohexose Fructoheptasaccharide SUCROSE MONOCAPRATE Sucrose stearate Fructo-oligosaccharide DP8 / GF7 Fructo-oligosaccharide DP9 / GF8 Fructo-oligosaccharide DP10/GF9 Sucrose SUCROSE TRISTEARATE Fructo-oligosaccharide DP8 Fructo-oligosaccharide DP12

  • 1-O-(1-O-β-D-Fructofuranosyl-β-D-fructofuranosyl)-β-D-fructofuranosyl α-D-glucopyranoside
  • 2-O-(2-O-α-D-Glucopyranosyl-1-deoxy-β-D-fructofuranose-1-yl)-1-deoxy-β-D-fructofuranose-1-yl β-D-fructofuranoside
  • (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-2-[[(2R,3S,4S,5R)-2-[[(2R,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxymethyl]-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-2-[[(2R,3S,4S,5R)-2-[[(2R,3S,4S,5R)-3,4-dihydroxy-2,5-dimethylol-tetrahydrofuran-2-yl]oxymethyl]-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]oxymethyl]-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-6-methylol-tetrahydropyran-3,4,5-triol
  • Nystose,β-D-Fruf-(2->1)-β-D-Fruf-(2->1)-β-D-Fruf-(2<-->1)-α-D-Glup
  • Nystose ,98%
  • Fungitetraose Nystose
  • 1)-b-D-fructofuranosyl
  • 1)-O-b-D-fructofuranosyl-(2&reg
  • a-D-Glucopyranoside, O-b-D-fructofuranosyl-(2&reg
  • 1)-α-D-Glup
  • 1)-β-D-Fruf-(2-&gt
  • 1)-β-D-Fruf-(2&lt
  • β-D-Fruf-(2-&gt
  • β-d-fruf-(2->1)-β-d-fruf-(2->1)-β-d-fruf-(2<->1)-α-d-glup
  • fungitetraose
  • NISTOSE
  • NYSTOSE
  • NistoseTrihydrate&gt
  • Fructo-oligosaccharide DP4/GF3
  • 1,1-Kestotetraose - 100mg
  • 1,1-Kestotetraose
  • a-D-Glucopyranoside, O-b-D-fructofuranosyl-(21)-O-b-D-fructofuranosyl-(21)-b-D-fructofuranosyl
  • α-D-Glucopyranoside, O-β-D-fructofuranosyl-(2→1)-O-β-D-fructofuranosyl-(2→1)-β-D-fructofuranosyl
  • NISTOSE USP/EP/BP
  • (2R,3R,4S,5S,6R)-2-(((2S,3S,4S,5R)-2-((((2R,3S,4S,5R)-2-((((2R,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Nystose (DP4) / GF3 (>98% HPAEC-PAD)
  • Nystose, 10 mM in DMSO
  • 13133-07-8
  • C24H42O213H2O
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