4,16-ANDROSTADIEN-3-BETA-OL
- Product Name
- 4,16-ANDROSTADIEN-3-BETA-OL
- CAS No.
- 23062-06-8
- Chemical Name
- 4,16-ANDROSTADIEN-3-BETA-OL
- Synonyms
- Fasedienol;Androsta-4,16-dien-3β-ol;4,16-ANDROSTADIEN-3-β-OL;4, 16-ANDROSTADIEN-3β-OL;Androsta-4,16-dien-3beta-ol;4,16-Anfrostadien-3-beta-OI;4,16-ANDROSTADIEN-3-BETA-OL;Androsta-4,16-dien-3-ol,(3b)-;Androsta-4,16-dien-3-ol, (3β)-;Androsta-4,16-dien-3β-ol (8CI)
- CBNumber
- CB4454436
- Molecular Formula
- C19H28O
- Formula Weight
- 272.42
- MOL File
- 23062-06-8.mol
4,16-ANDROSTADIEN-3-BETA-OL Property
- form
- Solid
- color
- White to off-white
- InChI
- InChI=1/C19H28O/c1-18-9-3-4-16(18)15-6-5-13-12-14(20)7-11-19(13,2)17(15)8-10-18/h3,9,12,14-17,20H,4-8,10-11H2,1-2H3/t14-,15-,16-,17-,18-,19-/s3
- InChIKey
- NYVFCEPOUVGTNP-KRHBYBJCNA-N
- SMILES
- [C@@H]1(O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C=CC3)CC2 |&1:0,4,8,10,12,14,r|
- CAS DataBase Reference
- 23062-06-8(CAS DataBase Reference)
4,16-ANDROSTADIEN-3-BETA-OL Chemical Properties,Usage,Production
Uses
Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON). Fasedienol significantly increases Ca++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety[1][2][3].
References
[1] Clive L. Jennings-White, et al. Steroids as neurochemical stimulators of the vno to alleviate symptoms of anxiety. Patent WO1998014194A1.
[2] Monti L, et al. Effect of fasedienol (PH94B) pherine nasal spray and steroidal hormones on electrogram responses and autonomic nervous system activity in healthy adult volunteers[J]. Human Psychopharmacology: Clinical and Experimental, 2024, 39(2): e2892. DOI:10.1002/hup.2892
[3] Monti L, et al. Neural circuits of anxiolytic and antidepressant pherine molecules. CNS Spectr. 2022 Feb;27(1):66-72. DOI:10.1017/S109285292000190X
4,16-ANDROSTADIEN-3-BETA-OL Preparation Products And Raw materials
Raw materials
Preparation Products
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